Page 31 - Differential Diagnosis in Small Animal Cytology, The Skin and Subcutis

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Pavement
Cells are flat, polygonal and arranged in thin layers
• Keratinocytes of the superficial layers of the epidermis and superior segment of the
hair follicle (infundibulum)
• Squamous cell carcinoma
• Papilloma

Acinar
Cells are cuboidal to columnar and arranged around a central pale area
• Sweat gland tumour
• Anal sac tumour

Palisade
Cells are cuboidal and arranged in regular rows
• Trichoblastoma
• Basal cell tumour
Ducts may cytologically mimic this type of arrangement (e.g. sweat gland duct adenoma)

Trabecular
Cells are arranged in branching cohesive clusters
• Perianal gland tumour

Fig. 3.1. Most common cytoarchitectures that can be found on cytology of cutaneous and subcutaneous lesions.
(1) Pavement. (2) Acinar. (3) Palisade. (4) Trabecular. (5) Perivascular. (6) Whorling. (7) Storiform. (Drawings courtesy
of Nic Ilchyshyn, DWR Diagnostic UK.)