Page 347 - Equine Clinical Medicine, Surgery and Reproduction, 2nd Edition
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322                                        CHAPTER 1



  VetBooks.ir  it should be noted that ultrasonography is much   tenotomy may be envisaged in the rare cases that do
                                                          not respond to conservative treatment.
           more operator dependent than MRI, providing an
           adequate protocol is used. MRI is particularly useful
           to detect or confirm osseous pathology at the origin  Hindlimb proximal suspensory desmopathy
           of the SL and has the advantage over ultrasound that   Conservative treatment may be applied as described
           the axial borders of the splint bones are clearly delin-  above. Even with prolonged rest, however, lameness
           eated. It is also sensitive to look for adhesions, char-  persists in 80% of cases. Compartment syndrome
           acterised by loss of the normal hyperintense border.   and  nerve damage have been suspected  to explain
           There is marked variation in the MRI appearance of   this lack of spontaneous improvement. The chances
           the SL and comparison with the contralateral limb   of a successful outcome are also markedly influenced
           may be warranted. Finally, MRI is less sensitive in   by the severity of the lesion, with better results to
           differentiating between chronic lesions and healed   be expected with localised ligamentous lesions and
           desmitis. Interpretation must therefore be carefully   osseous lesions decreasing the chances of full recov-
           weighed against the clinical appraisal and a multi-  ery. Radial shock-wave therapy has been shown to
           modality approach (i.e. MRI and ultrasonography) is   improve the clinical signs (lameness) in a significant
           probably most efficient.                       proportion of animals, with 41% of cases returning
                                                          to work after 6 months in one study. The ultrasono-
           Management                                     graphic appearance of the lesion remained unaltered.
           Forelimb proximal suspensory ligament          Its mode of action is thought to be analgesia through
           desmopathy                                     destruction of nerve endings. Extracorporeal shock-
           Conservative treatment  is  undertaken  as  for  SDF   wave therapy probably helps in the early stages by
           tendinopathy. It is based on initial box rest with in-  providing analgesia.
           hand walking for 5–10 minutes 2–4 times daily for   Other forms of physiotherapy have generally not
           4 weeks, then gradually increasing to 20 minutes   been effective in this condition. Many cases have
           in-hand  walking  or in  a mechanical  walker over  a   very poor foot conformation and will benefit from
           4–8 week period. Local hydro- or cryotherapy may   corrective foot trimming and shoeing.
           be used in combination. Pressure bandages may be   Periligamentous injection using corticosteroids
           useful in the early stages. Foot balance should be   has been used extensively and may decrease swell-
           addressed, and some relief may be obtained with the   ing and compartment syndrome in the early stages;
           use of shoes set long and wide at the heels or bar   however, it may also be detrimental as decreased
           shoes. Follow-up ultrasonography should be per-  cell metabolism and acute injury are rarely encoun-
           formed at 8 weeks. Some acute injuries in the fore-  tered. Polysulphated glycosaminoglycans and hyal-
           limbs will allow a gradual return to work between 3   uronic acid treatments have lead to disappointing
           and 6 months post injury. Full work should not be   results.
           resumed before complete resolution of the lesion   Intralesional biological treatments are popular
           on ultrasonography. In chronic cases the lesion may   but as yet there are very few published reports to
           persist; if this is the case, return to work is based on   support their efficacy. Autologous MSCs isolated
           the absence of evolution of the lesion on ultrasonog-  from  bone  marrow  or  adipose  tissue,  heterolo-
           raphy for a period of 3 months. Surgical options or   gous stem cells obtained from equine fetal tissue
           intraligamentous injections of corticosteroids, hyal-  or adult tendon, PRP and porcine urinary bladder
           uronate or glycosaminoglycans have not been shown   matrix (UBM) powder (A-Cell ) are being used but
                                                                                    ®
           to improve the outcome, which is considered good to   there is mostly circumstantial evidence of mark-
           excellent with up to 90% of the horses returning to   edly  improved  success  rates  compared  with  other
           their previous level of exercise. Bone marrow injec-  treatments.
           tions, MSCs and microdrilling (‘osteostixis’) have   Surgically based treatments include fasciotomy to
           all been advocated but are rarely indicated in the   relieve the compartment syndrome, specific neurec-
           forelimb. Microdrilling combined with longitudinal   tomy of the deep branch of the lateral plantar nerve
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