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494   Hyperemia




            Hyperemia                                                                               Bonus Material
                                                                                                         Online
  VetBooks.ir                                                                    Initial Database

            BASIC INFORMATION
                                                on the underlying cause. Hyperemia usually
                                                manifests as erythema (redness of the skin   •  Temperature, heart rate, respiration rate
           Definition                           and mucous membranes)  due to  vessel   ○   Hyperthermia warrants consideration of
           •  Active hyperemia: increased volume of blood   engorgement with oxygenated blood.  true fever (e.g., infectious, inflammatory,
            in an affected tissue or area due to arterial   •  Generalized hyperemia  drug reaction, neoplastic causes) versus
            dilation                            ○   Tachycardia, tachypnea, hyperthermia  environmental  hyperthermia (e.g., hot
           •  Passive hyperemia: increased volume of blood   ○   Increased respiratory effort  weather, thick haircoat, anxiety, tremor).
            in an affected tissue or area due to venous   ○   Shortened capillary refill time  •  Diascopy:  superficial  lesions  blanch  with
            distention                          ○   Episodic increased levels of activity  external pressure, such as with a glass slide.
                                              •  Localized hyperemia               ○   This maneuver helps confirm whether
           Synonyms                             ○   Regional dermal redness, swelling, and/  hyperemia is present versus normal
           •  Active hyperemia: arterial hyperemia, reactive   or pain               coloration  or an  area of  subcutaneous
            hyperemia, metabolic hyperemia      ○   Site may be warmer than normal and less   hemorrhage.
           •  Passive hyperemia: venous hyperemia  functional
                                                                                 Advanced or Confirmatory Testing
           Epidemiology                       Etiology and Pathophysiology       Use  of  these  tests  depends  on  determination
           SPECIES, AGE, SEX                  •  Arteriolar  dilation  usually  is  in  response   of  need.  For  example, in animals  that  are
           Any dog or cat                       to tissue hypoxia, sympathetic neurogenic   otherwise clinically normal (routine exam),
                                                mechanisms, and/or exposure to vasodilatory   behavioral agitation/anxiety, benign environ-
           RISK FACTORS                         metabolites released locally or systemically,   mental hyperthermia, and exercise are common
           •  Increased  tissue  metabolic  demand  (e.g.,   such as adenosine, nitric oxide, lactate,   causes of hyperemia that do not warrant further
            fever, physical exertion)           potassium ion, and carbon dioxide.  evaluation.
           •  Vascular   occlusion:   extravascular   or   •  Venous  distention,  however,  occurs  in   •  Blood pressure measurements (p. 1065)
            intravascular                       response  to obstruction  of blood  outflow   ○   Systemic
                                                due to obstruction within the capillaries   ○   Localized (if embolic occlusion suspected)
           GEOGRAPHY AND SEASONALITY            or veins due to thickening of the walls or   •  CBC (infectious, inflammatory, neoplastic,
           Vasodilatory cooling related to high envi-  thrombi or to external pressure such as from   polycythemia)
           ronmental temperature is a normal cause of   a tumor or tight bandaging.  •  Serum  biochemistry  panel  (hepatic,  renal
           hyperemia.                                                              dysfunction)
           Clinical Presentation               DIAGNOSIS                         •  Radiographs (organomegaly, neoplasia)
                                                                                 •  Neurologic evaluation (in cases of suspected
           DISEASE FORMS/SUBTYPES             Diagnostic Overview                  intoxication or other systemic disorders with
           •  Primary complaint               Hyperemia is a clinical sign associated with a   neurologic effects) (p. 1136)
            ○   Obvious extravascular occlusion such as   wide variety of conditions. Rule out obvious   •  Abdominal ultrasound (neoplasm, infection/
              limb constriction               causes by a careful history and physical exam   abscess, chronic passive congestion)
            ○   Gross tissue changes          and determine whether the presence of hyper-  •  Echocardiogram  (endocarditis,  embolic
           •  Secondary finding               emia is clinically significant.      disorder, other [p. 1094])
            ○   Abnormal finding during examination                              •  Aspirates and/or biopsies (masses, lesions)
              prompted by another problem     Differential Diagnosis             •  Tick-borne disease titers
            ○   Incidental finding of no clinical sig-  Hyperemia (p. 1234)      •  Blood gas analysis
              nificance (e.g., due to anxiety, physical
              activity, hot weather)
           •  Hyperemia may also be classified as regional
            or generalized.

           HISTORY, CHIEF COMPLAINT
           •  Highly  variable  depending  on  underlying
            cause
           •  Examples of generalized hyperemia
            ○   Recent exposure to allergen (e.g., insect
              bite, vaccine, food allergen)
            ○   Exposure  to toxic  agent (e.g.,  smoke
              inhalation)
            ○   Exposure to high environmental tempera-
              ture (e.g., thick haircoat, locked in car)
            ○   Systemic disease (e.g., pheochromocytoma,
              mast cell disease, shock)
            ○   Anxiety, restlessness (incidental finding
              during routine exam)
           PHYSICAL EXAM FINDINGS             HYPEREMIA  Conjunctival hyperemia in a 5-year-old shih tzu. The image was captured from a digital movie
           •  Because hyperemia is a clinical sign and not   clip obtained by the owner at home. The chief complaint was episodic restlessness and generalized hyperemia,
            a disease entity, physical findings depend   noted intermittently by the owner for a period of weeks. (Courtesy Dr. Etienne Côté.)

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