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Hyperestrogenism, Canine 495.e3

VetBooks.ir Diseases and Disorders

HYPERESTROGENISM Alopecia in a bilateral cryptorchid male miniature pinscher with a Sertoli cell tumor. HYPERESTROGENISM Alopecia in a bilateral
Note the noninflammatory alopecia of the abdomen, flank, and lateral thorax and neck. (Copyright Dr. María cryptorchid male miniature pinscher with a Sertoli
Soledad González-Domínguez.) cell tumor. Note the noninflammatory alopecia of the
caudomedial aspect of the thighs. (Copyright Dr. María
Soledad González-Domínguez.)

PEARLS & CONSIDERATIONS neutered dogs, always looks at nipple size (and Grootenhuis AJ, et al: Inhibin, gonadotrophins and
vulva in female) because their enlargement is sex steroids in dogs with Sertoli cell tumours.
Comments highly suggestive of hyperestrogenism. Endocrinology 127(2):235-242, 1990.
• An acquired symmetrical, noninflammatory Gross TL, et al, editors: Skin diseases of the dog and
alopecia associated with gynecomastia and/or SUGGESTED READINGS cat: clinical and histopathologic diagnosis, ed 2,
Ames, Iowa, 2005, Blackwell Science.
testicular abnormalities (particularly cryptor- Mecklenburg L: Canine hyperestrogenism. In Liao AT, et al: A 12-year retrospective study of canine
chidism) is very suggestive of hyperestrogenism. Mecklenburg L, et al, editors: Hair loss disorders testicular tumors. J Vet Med Sci 71(7):919-923,
• It is highly probable that cryptorchid males in domestic animals, Ames, Iowa, 2009, Wiley- 2009.
exhibiting noninflammatory alopecia are Blackwell, pp 129-134. Miller WH: Muller & Kirk’s small animal dermatol-
affected by hyperestrogenism. Wiener DJ, et al: Estradiol-induced alopecia in five ogy, ed 7, St. Louis, 2013, Elsevier, pp 590-592.
• Measuring estrogen levels is of limited value. dogs after contact with a transdermal gel used for
the treatment of postmenopausal symptoms in RELATED CLIENT EDUCATION
Prevention women. Vet Dermatol 26(5):393-e91, 2015.
• Avoid direct exposure of pets to topical ADDITIONAL SUGGESTED SHEETS
human medications. Consent to Perform Abdominal Ultrasound
• Use estrogen therapies with care. READINGS Consent to Perform Castration, Canine
• Consider neutering pets not used for Berger DJ, et al: Canine alopecia secondary to Consent to Perform Ovariohysterectomy (Spay),
breeding. human topical hormone replacement therapy in Canine
six dogs. J Am Anim Hosp Assoc 51(2):136-142,
Technician Tips 2015. AUTHOR: María Soledad González-Domínguez, MV,
When presented with a dog with a symmetrical, Frank LA: Comparative dermatology—canine endo- Esp, MSc
crine dermatoses. Clin Dermatol 24(4):317-325,
noninflammatory alopecia, particularly in 2006. EDITOR: Manon Paradis, DMV, MVSc, DACVD

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