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Intracranial Neoplasia   557


           •  Urine  scalding  of  skin  from  overflow   decompression. However, the time frame for   overflow from a distended bladder can give
             incontinence                       recovery is extremely variable (few days to   caretakers the mistaken impression that the
  VetBooks.ir  spinal cord trauma or vascular changes during   •  With nonsurgical treatment about 85% of   •  Ongoing monitoring is essential to determine   Diseases and   Disorders
                                                many weeks or months).
                                                                                    dog is urinating frequently.
           •  Worsened neurologic status due to iatrogenic
                                                ambulatory and 60% of non-ambulatory (but
                                                                                    whether the current treatment course should
             decompressive surgery
           •  Intraoperative  hemorrhage  or  respiratory
                                                                                    of signs, or worsening of signs make a new
             arrest requiring ventilator support during   retaining pain perception) dogs ultimately   be continued or if failure to improve, relapse
                                                recover.
             ventral slot for cervical decompression  •  The recurrence rate (i.e., new disc extrusion   strategy advisable.
           •  Ascending-descending  myelomalacia:  dev-  at a different level) is low in nonchondro-  •  Referral to a veterinary neurology or surgical
             astating complication that occurs in < 1% of   dystrophic breeds, although some of these   specialist should be offered if surgery is to
             acutely paraplegic dogs. Focal lesion, usually   dogs (especially German shepherds) may have   be considered.
             T3-L3 (perhaps more common with lower   signs attributable to Hansen type II disease
             lumbar disc extrusions), rapidly deteriorates   at multiple levels simultaneously.  Prevention
             to expanding  cord necrosis,  causing signs   •  For chondrodystrophic breeds treated with   •  Avoidance of obesity and jumping activities
             of ascending and/or descending cord dys-  surgical decompression, recurrence rates vary   for chondrodystrophic breeds may lessen the
             function over a period of hours. There is   between 5% and 25%.        tendency for recurrence.
             no known treatment for this complication,   •  The recurrence rate for medically managed   •  Prophylactic disc fenestration or chemonucle-
             and the key is early recognition so humane   patients is about 40%.    olysis may reduce the risk of disc extrusion
             euthanasia can be performed.      •  Dogs with signs attributable to ascending-  for treated disc spaces, but risks and the true
                                                descending myelomalacia have a grave   benefit are unproven at this time.
           Recommended Monitoring               prognosis.
           Discomfort level, bladder/bowel evacuations,                           Technician Tips
           evidence of pressure sores, and neurologic    PEARLS & CONSIDERATIONS  Close monitoring  of bladder  function  and
           status, including evidence of myelomalacia,                            bladder expression or catheterization is impor-
           should be assessed frequently until the patient   Comments             tant to prevent overdistention of bladder and
           has recovered.                      •  Strict cage rest is critical for recovery in non-  detrusor atony. Check bladder size regularly,
                                                surgical patients treated only with analgesics   even in dogs that seem to be urinating, because
            PROGNOSIS & OUTCOME                 and antiinflammatory medications. Physical   overflow incontinence can be deceptive.
                                                rehabilitation, weight control, and avoidance
           •  The most important prognostic indicator for   of jumping activities may reduce the risk of   Client Education
             dogs without voluntary motor function is   recurrence and future need for surgery.  •  See Prevention above.
             the presence or absence of nociception (deep   •  There is no direct correlation between severity   •  For  paralyzed  patients,  clients  should  be
             pain  sensation)  because  the  unmyelinated   of signs and amount of disc material dis-  informed  about  bladder  expression  and
             pain fibers in the spinal cord are the least   placed. Dogs with pain as their only sign or   nursing care to understand this component
             vulnerable to ischemic injury. This assessment   those with only mild deficits may have large   of management.
             is  always  subjective,  but  apparent  loss  of   amounts of displaced disc and marked spinal
             sensation caudal to the level of spinal cord   cord/nerve root compression. Conversely,   SUGGESTED READING
             injury suggests the possibility for permanent   some of the most severely affected dogs may   Dewey  CW:  Surgery  of  the  cervical  and  thora-
             paralysis, regardless of treatment. Approxi-  have suffered a low-volume/high-velocity   columbar  spine.  In  Fossum  TW,  editor:  Small
             mately 60% of dogs in this condition recover   extrusion, which is not likely to be improved   animal surgery, ed 4, St. Louis, 2013, Mosby, pp
             if treated with decompressive surgery.  by surgery, even if done on an emergency   1467-1507, 1508-1528.
           •  90%-97% of dogs with intact nociception,   basis.                   AUTHOR: Suresh Sathya, BVSc, MVSc, MVetSc
             even if they are paraplegic or tetraplegic,   •  Dogs with thoracolumbar disc disease are   EDITOR: Kathleen Linn, DVM, MS, DACVS
             recover fully or almost fully with surgical   often unable to urinate, but the resultant






            Intracranial Neoplasia                                                                 Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  Synonyms                             develop meningiomas. Brachycephalic breeds
                                               Brain neoplasia; brain tumor         (e.g., boxer, Boston terrier) appear prone to
           Definition                                                               developing gliomas.
           •  Primary brain tumors include meningioma,   Epidemiology             •  Feline: no breed predisposition. Meningioma is
             glioma (astrocytoma, oligodendroglioma),   SPECIES, AGE, SEX           the most common brain tumor in cats (≈60%).
             choroid plexus tumor, ependymoma, medul-  •  Dogs and cats of both sexes  Clinical Presentation
             loblastoma, olfactory neuroblastoma, and   •  Incidence reported as high as 2.6% for dogs
             primitive neuroectodermal tumor.   and 2.8% for cats                 DISEASE FORMS/SUBTYPES
           •  Secondary  brain  tumors  include  pituitary   •  Brain tumors typically occur in older dogs   •  Meningioma:  tumor  of  the  arachnoid
             tumors, tumors that invade by direct   (most > 7 years old) and cats. Median age:   membrane
             extension into the brain (e.g., nasal tumors,   9 years (dogs), 11 years (cats)  •  Glioma:  tumor  of  the  cells  that  form  the
             multilobular tumor of bone, osteosarcoma),                             interstitial tissue of the central nervous
             and  metastatic  tumors  to  the  brain  (e.g.,   GENETICS, BREED PREDISPOSITION  system (CNS)
             hemangiosarcoma, lymphoma).       •  Canine: dolichocephalic breeds (e.g., golden   •  Choroid  plexus  papilloma:  tumor  of  the
                                                retriever, German shepherd dogs) tend to   cells of the choroid plexus, the intracranial

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