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Otitis Externa   729


           Initial Database                    Advanced or Confirmatory Testing   •  Resolve infection with topical otic antimicro-
                                                                                    bial agents, and monitor response to therapy.
           •  Physical  exam:  to  identify  the  underlying   •  Video  otoscopy  (p.  1144)  allows  greater   •  Prevent recurrence by diagnosing and manag-
  VetBooks.ir  In the dog, the most common causes are   •  Radiographic imaging: plain radiology, CT,   ing the primary cause, perpetuating causes,   Diseases and   Disorders
                                                visualization and detail resolution of the
             dermatologic disease that triggered the otitis.
                                                ear canal and tympanic membrane.
             allergic diseases (e.g., cutaneous adverse food
                                                                                    and predisposing factors.
             reaction, atopic dermatitis), and in the cat,
                                                middle, and internal parts of the ear.
             O. cynotis and nasopharyngeal polyps are   and  MRI  are  used  to  image  the  external,   Mainstay of therapy for otitis externa is topical
                                                                                  otic therapy, with the choice of topical otic
             more common primary causes of otitis than   Abnormal findings indicate otitis media,   medication based on
             allergies.                         but normal radiographic findings  do not   •  Results of otic cytology are used to choose
           •  Otic exam: to evaluate the vertical and hori-  rule out otitis media.  the  active  ingredient  in  the  topical  otic
             zontal ear canal for evidence of hyperplasia,   •  Ear  flush  under  anesthesia:  to  completely   medication.
             stenosis, and ulceration, as well as to evaluate   clean the external ear canal when further   ○   Options for bacterial otitis externa
             the amount, consistency, and color of the otic   exam is needed          include aminoglycosides, polymyxin B,
             exudate. If possible, the tympanic membrane   •  Audiologic  testing:  brainstem  auditory   florfenicol, silver sulfadiazine, tris-EDTA,
             is examined.                       evoked  response  (BAER)  testing  is  an   and fluoroquinolones.
           •  Otic cytology:  CRITICAL diagnostic test is   objective test used to measure the animal’s   ○   Options for yeast otitis externa include
             used for identification of bacterial (rods,   auditory response to sound stimulation.  nystatin, thiabendazole, clotrimazole,
             cocci) and yeast organisms and for leuko-  •  Allergy  workup:  elimination  diet  trial;   miconazole, ketoconazole, posaconazole,
             cytes. Any rod bacteria detected cytologically   intradermal allergy testing, and serum allergy   and terbinafine.
             should be considered abnormal.     testing (pp. 91 and 345)          •  Results of the otic exam are used for selection
           •  Ear  swab:  mite  identification.  A  second   •  Neurologic exam (p. 1136)  of the vehicle of the topical otic medication.
             sample should be obtained from each ear   •  Mass removal/biopsy       ○   Solution, lotion, emulsion, flush, or gel if
             and mixed with mineral oil to assess for                                 the ear canals range from no stenosis and
             Otodectes and Demodex mites.       TREATMENT                             hyperplasia to moderate to severe stenosis
           •  Otic  culture:  bacterial  culture  and  sus-                           and/or hyperplasia
             ceptibility testing is done to identify the   Treatment Overview       ○   Suspension or ointment if there is minimal
             organism(s) in the ear and to guide the use   Goals of management of otitis externa:  or no stenosis or hyperplasia
             of systemic (oral) antimicrobial therapy   •  Reduce inflammation of the ear canal with   •  Chronicity of the otitis is used to select the
             because the results indicate the attainable   glucocorticoids.         specific topical otic medication.
             levels in the plasma. Susceptibility testing is   •  Clean  the  ear  by  having  the  owner  use   ○   Acute or occasional otitis externa: first-line
             generally not clinically useful for determining     an otic cleaning and drying agent at   topical otic medication
             the appropriate topical otic antimicrobial   home or by an in-hospital ear flush under     ○   Chronic otitis externa: second-line topical
             agent.                             anesthesia.                           otic medication







            Topical Otic Treatments for Otitis Externa
                                                     PRODUCT OPTIONS FOR ORGANISMS CYTOLOGICALLY DETECTED
                                 Rods, Cocci, and Yeast or
            Otic Exam            Rods and Yeast or Rods  Cocci and Yeast or Cocci Only  Yeast
            Treatment of Acute Otitis Externa
            Minimal or no stenosis or   •  EasOtic suspension  •  Claro otic solution  •  Claro otic solution
            hyperplasia; first-line topical   •  Mometamax suspension  •  EasOtic suspension  •  EasOtic suspension
            otic medication, active   •  Otomax ointment  •  Mometamax suspension  •  MalAcetic Ultra otic flush*
            ingredients based on cytologic   •  Surolan suspension  •  Osurnia otic gel  •  Mal-A-Ket plus TrizEDTA flush*
            evaluation of otic exudate   •  Tresaderm solution*  •  Otomax ointment  •  Miconazole 1% lotion †
            containing any vehicle                    •  Surolan suspension        •  Miconazole 1% lotion/dexamethasone (2 mg/mL
                                                                                           †
                                                      •  Tresaderm solution*         injectable)  (1 : 1 vol. conc.), extralabel
                                                                                   •  Mometamax suspension
                                                                                   •  Osurnia otic gel
                                                                                   •  Otomax ointment
                                                                                   •  Surolan suspension
                                                                                   •  Tresaderm solution*
                                                                                   •  TrizUltra + Keto flush*
                                                                                   •  T8 Keto flush*
            Moderate to severe stenosis   •  Tresaderm solution*  •  Claro otic solution  •  Claro otic solution
            or hyperplasia; first-line                •  Osurnia otic gel          •  Mal-A-Ket plus TrizEDTA flush*
            topical otic medication, active           •  Tresaderm solution*       •  Miconazole 1% lotion †
            ingredients based on cytologic                                         •  Miconazole 1% lotion/dexamethasone (2 mg/mL
                                                                                           †
            evaluation of otic exudate                                               injectable)  (1 : 1 vol. conc.), extralabel
            containing solution, lotion,                                           •  Osurnia otic gel
            emulsion, flush, or gel vehicle                                        •  Tresaderm solution*
                                                                                   •  TrizUltra + Keto flush*
                                                                                   •  T8 Keto flush*
                                                                                                            Continued

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