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732   Ovarian Remnant Syndrome





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           OTODECTIC MANGE  Gross appearance of a young cat with otodectic mange.
           The pinna appears normal, but copious specks of characteristic exudate (“coffee   OTODECTIC MANGE  Microscopic appearance of ear mites (Otodectes cynotis).
           grounds”) are visible in the ear canal. (Copyright Dr. Manon Paradis, University   (Copyright Dr. Manon Paradis, University of Montreal.)
           of Montreal.)

           Isoxazolines:                       PROGNOSIS & OUTCOME               Technician Tips
           •  Dogs                                                               Diagnosis may be falsely based on typical
            ○   Fluralaner (Bravecto 25 mg/kg PO) as a   Excellent               appearance  of otic exudate  alone, without
              single oral dose                                                   visualization of parasites on microscopy. This
            ○   Sarolaner (Simparica 2 mg/kg PO) as a    PEARLS & CONSIDERATIONS  is often misleading.
              single oral dose or 2 treatments 30 days
              apart                           Comments                           Client Education
           •  Cats                            •  Other  household  pets  such  as  ferrets  can   Many  pet  owners  seeing  inflamed  ears  with
            ○   Fluralaner (Bravecto spot-on solution,   become infested.        discharge assume it is an ear mite infestation,
              40 mg/kg) applied topically once  •  Ear mites can be eradicated only if all animals   often leading to weeks of inappropriate treat-
            ○   A combination of selamectin plus sarolaner   in contact are treated simultaneously, even   ment with over-the-counter treatments.
              spot-on  formulation  (Revolution  Plus,   if signs of disease are absent.
              Stronghold Plus) applied topically once                            SUGGESTED READING
                                              Prevention
           Drug Interactions                  •  Ear  mites  have  a  3-week  life  cycle  and  a   Taenzler J, et al: Efficacy of fluralaner against Otodectes
                                                                                   cynotis infestations in dogs and cats. Parasit Vectors
           Off-label doses of ivermectin or moxidectin   2-month life span. They can live off the   10(1):30, 2017.
           should not be used in sensitive canine breeds   host for weeks. Environment may require   AUTHOR: Vincent E. Defalque, DVM, DACVD
           unless the MDR1/ABCB1-Δ gene mutation is   thorough cleaning and treatment in cattery   EDITOR: Manon Paradis, DMV, MVSc, DACVD
           confirmed to be absent (p. 638).     or kennel situations.
                                              •  When Revolution/Stronghold or Advantage
           Possible Complications               Multi/Advocate  is  used  as  flea  control,  it
           Otitis media                         has the added benefit of ongoing ear mite
                                                prevention.
           Recommended Monitoring
           Repeat ear swab and physical exam 1 month
           after first treatment if clinical signs persist.




            Ovarian Remnant Syndrome


                                              Epidemiology                       GENETICS, BREED PREDISPOSITION
            BASIC INFORMATION
                                              SPECIES, AGE, SEX                  Large-breed dogs may have increased incidence.
           Definition                         Female dog or cat; months to years after
           Presence of functional ovarian tissue in a previ-  ovariectomy  (OVE)  or  ovariohysterectomy     RISK FACTORS
           ously ovariectomized bitch or queen  (OHE)                            OVE during estrus or at time of cesarean section
                                                                                 may increase risk.

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