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730   Otitis Externa



            Topical Otic Treatments for Otitis Externa—cont’d
  VetBooks.ir  Otic Exam        Rods, Cocci, and Yeast or   PRODUCT OPTIONS FOR ORGANISMS CYTOLOGICALLY DETECTED

                                                      Cocci and Yeast or Cocci Only
                                                                                  Yeast
                                Rods and Yeast or Rods
            Treatment of Chronic Otitis Externa
            Minimal or no stenosis or   •  Baytril (2.27% injectable)/  •  Baytril (2.27% injectable)/Cort/Astrin   •  Claro otic solution
            hyperplasia; second-line   miconazole 1% lotion/  solution  (1 : 4 vol. conc.), extralabel  •  EasOtic suspension
                                                            †
            topical otic medication, active   dexamethasone (2 mg/mL   •  Baytril (2.27% injectable)/ dexamethasone   •  MalAcetic Ultra otic flush*
            ingredients based on cytologic   injectable) solution  (1 : 1 : 1   (2 mg/mL injectable)/ saline solution   †  •  TrizEDTA flush*
                                            †
            evaluation of otic exudate   vol. conc.), extralabel  (1 : 1 : 1 vol. conc.), extralabel  •  Miconazole 1% lotion †
            containing any vehicle  •  Posatex suspension  •  Baytril otic emulsion  •  Miconazole 1% lotion/dexamethasone (2 mg/mL
                                                                                          †
                                                      •  Posatex suspension         injectable)  (1 : 1 vol. conc.), extralabel
                                                                                  •  Mometamax suspension
                                                                                  •  Osurnia otic gel
                                                                                  •  Otomax ointment
                                                                                  •  Tresaderm solution*
                                                                                  •  TrizUltra + Keto flush*
                                                                                  •  T8 Keto flush*
            Moderate to severe stenosis   •  Baytril (2.27% injectable)/   •  Baytril (2.27% injectable): Cort/Astrin   •  Claro otic solution
                                                            †
            or hyperplasia; second-line   miconazole 1% lotion/   solution  (1 : 4 vol. conc.), extralabel  •  MalAcetic Ultra otic flush*
            topical otic medication, active   dexamethasone (2 mg/mL   •  Baytril (2.27% injectable)/ dexamethasone   •  TrizEDTA flush*
                                            †
            ingredients based on cytologic   injectable) solution  (1 : 1 : 1   (2 mg/mL injectable)/ saline solution   †  •  Miconazole 1% lotion †
            evaluation of otic exudate   vol. conc.), extralabel  (1 : 1 : 1 vol. conc.), extralabel  •  Miconazole 1% lotion/dexamethasone (2 mg/mL
                                                                                          †
            containing solution, lotion,              •  Baytril otic emulsion      injectable)  (1 : 1 vol. conc.), extralabel
            emulsion, flush, or gel vehicle                                       •  Osurnia otic gel
           *Products for use in cats.
           † Products not specifically for use in the ear.
           -Active ingredients of otic products:
                                                  †
           Baytril (2.27% injectable)/dexamethasone (2 mg/mL injectable)/saline solution  (1 : 1 : 1 vol. conc.), extralabel
                                                         †
           Baytril (2.27% injectable)/miconazole 1% lotion/dexamethasone (2 mg/mL injectable) solution  (1 : 1 : 1 vol. conc.), extralabel
                                 †
           Baytril (2.27% injectable): Cort/Astrin solution : (1 : 4 vol. conc.), extralabel
           Baytril otic emulsion: enrofloxacin, silver sulfadiazine
           Claro otic solution: florfenicol, terbinafine, mometasone furoate
           EasOtic suspension: gentamicin sulfate, miconazole, hydrocortisone aceponate
           MalAcetic Ultra otic flush*: ketoconazole, acetic acid, boric acid, hydrocortisone
           Mal-A-Ket plus TrizEDTA flush*: chlorhexidine gluconate, ketoconazole, tris-EDTA
           Miconazole 1% lotion †
                                        †
           Miconazole 1% lotion/dexamethasone (2 mg/mL injectable) (1 : 1 vol. conc.), extralabel
           Mometamax suspension: gentamicin sulfate, clotrimazole, mometasone furoate
           Osurnia otic gel: florfenicol, terbinafine, betamethasone acetate
           Otomax ointment: gentamicin sulfate, clotrimazole, betamethasone valerate
           Posatex suspension: orbifloxacin, posaconazole, mometasone furoate
           Surolan suspension: miconazole, polymyxin B, prednisolone
           T8 Keto flush*: tris-EDTA, ketoconazole
           Tresaderm solution*: neomycin sulfate thiabendazole, dexamethasone
           TrizUltra + Keto flush*: ketoconazole, tris-EDTA
            Additional Topical Medications for Acute or Chronic Otitis Externa   Chronic Treatment
                                                                                 In end-stage otitis, the ear canal is completely or
            •  Ear cleaning and drying agents
              •  Recommended for at-home cleaning                                nearly completely occluded, often accompanied
              •  May be used daily or as needed                                  by palpable fibrosis/mineralization, and is non-
            •  Ceruminolytic agent                                               responsive to treatment with glucocorticoids.
              •  Used for in-clinic anesthetic flush or at-home cleaning         Treatment  at  that  point  is  surgical  total  ear
              •  Ceruminolytic agents are considered ototoxic until proved otherwise  canal ablation and bulla osteotomy.
              •  Non-ototoxic product option
               •  Cerumene* (25% squalene)                                       Possible Complications
            •  Glucocorticoids                                                   Para-aural abscesses, draining tracts, infectious
              •  Used if specific otic medication for infection does not contain a glucocorticoid  otitis media, and otitis interna
              •  Used for management of allergic otitis externa
              •  Product options                                                 Recommended Monitoring
               •  Cort/Astrin* (Burow’s solution, 1% hydrocortisone)
               •  Synotic (0.01% fluocinolone acetonide, 60% dimethyl sulfoxide)  An otoscopic exam along with otic cytology
            •  Tris-EDTA                                                         should be performed by the veterinarian every
              •  Recommend using a tris-EDTA–containing product any time the otic infection is due to rod (gram-  2 to 4 weeks to monitor improvement in the
               negative) bacteria                                                clinical signs of the otitis and resolution of
              •  Pre-treat before using a specific otic medication for the bacterial infection  the infection.
              •  Product options
               •  Mal-A-Ket plus TrizEDTA flush*: chlorhexidine gluconate, ketoconazole, tris-EDTA
               •  TrizUltra + Keto flush*: ketoconazole, tris-EDTA                PROGNOSIS & OUTCOME
               •  T8 Keto flush*: tris-EDTA, ketoconazole
               •  TrizChlor flush*: chlorhexidine, tris-EDTA                     If the primary cause of the otitis externa is
                                                                                 identified and managed, the prognosis is good.
            *Products for use in cats.                                           Causative primary factors for otitis externa must
            † Products not specifically for use in the ear.
                                                                                 be evaluated or the condition is likely to become
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