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Pulse Abnormalities   845


           coronary artery is suspected, a left-sided injec-  feasible, exercise restriction and beta-blocker    PEARLS & CONSIDERATIONS
           tion should be performed to assess coronary   therapy  are  frequently  recommended  to   Comments
  VetBooks.ir  rupture  during  balloon  valvuloplasty.  These   sudden  death, although the  latter benefit   Careful auscultation over the left heart base   Diseases and   Disorders
                                                control clinical signs and reduce the risk of
           anatomy due to the risk of coronary artery
                                                remains unproven.
           abnormalities  are  most  commonly  reported
                                                                                  is key to detection, especially in animals with
           in boxers and bulldog breeds.
                                               Possible Complications             no clinical signs.
            TREATMENT                          In severe obstruction, progressive right ven-  Prevention
                                               tricular hypertrophy, tricuspid regurgitation,   Dogs with confirmed pulmonic stenosis should
           Treatment Overview                  and increased right atrial pressure may result in   not be used for breeding.
           The goal of treatment is to reduce clinical signs   worsening exercise tolerance, recurrent syncope,
           and myocardial workload to decrease the risk   arrhythmias, CHF, and sudden death.  Technician Tips
           of CHF and sudden death.                                               Common signs of disease progression include
                                               Recommended Monitoring             the development or worsening of exercise
           Acute General Treatment             For dogs not undergoing interventional or   intolerance or arrhythmias, increasing frequency
           •  Treatment is not necessary in animals with   surgical treatment, serial echocardiography   of syncope, and development of clinical signs
             mild or moderate stenosis that is not associ-  is recommended to monitor progressive   of right-sided CHF, such as ascites. Situations
             ated with clinical signs.         right ventricular hypertrophy or right atrial   likely to result in increased sympathetic tone
           •  Animals with severe, fixed obstruction and/or   enlargement. The pressure gradient sometimes   (e.g., stress, excitement, exertion) should be
             clinical signs referable to pulmonic stenosis   increases as puppies grow toward maturity. After   avoided in cases of severe pulmonic stenosis
             (e.g., exercise intolerance, syncope or signs   interventional or surgical treatment, short- and   because they are likely to exacerbate clinical
             of right-sided CHF) should be referred for   long-term success is assessed by longitudinal   signs. Calm, gentle handling is paramount,
             interventional or surgical reduction in pres-  echocardiographic monitoring of the pressure   especially for cats.
             sure gradient. The precise approach chosen   gradient.  Detected  arrhythmias  should  be
             (e.g., balloon valvuloplasty, pulmonary patch   assessed and monitored electrocardiographically.  Client Education
             graft) depends on the anatomic location and                          Puppies with persistent heart murmurs often
             characteristics of the lesion and presence or    PROGNOSIS & OUTCOME  benefit from referral to a veterinary cardiologist
             absence of concurrent congenital defects.                            for echocardiography. Balloon valvuloplasty or
           •  Type 1 valvular lesions are most amenable   •  Animals with mild pulmonic stenosis often   surgical correction should be offered in cases of
             to balloon valvuloplasty. Surgery may be   have a good quality of life and relatively   severe stenosis. Owners should be warned of
             necessary in cases of annular hypoplasia or   normal life expectancy.  the risk of right-sided CHF or sudden death
             significant subvalvular obstruction.  •  Prognosis  is  guarded  for  dogs  with  severe   in these cases.
           •  Dynamic obstructions that are exacerbated   obstructions due to the risk of right-sided
             by increased sympathetic tone may respond   CHF or sudden death. Prognosis is also nega-  SUGGESTED READING
             to adrenergic beta-receptor blockade (e.g.,   tively affected by significant right ventricular   Stafford JM, et al: Pulmonic stenosis in dogs: balloon
             atenolol 0.5-1.5 mg/kg PO q 12h). These   hypertrophy or tricuspid regurgitation.  valvuloplasty improves outcome. J Vet Intern Med
             dynamic  obstructions  may  persist  after   •  Balloon  valvuloplasty  improves  outcome,   18:656-662, 2004.
             interventional or surgical treatment for fixed   especially in those patients in which severity   AUTHOR: Melanie Hezzell, VetMB, MA, PhD, DACVIM
             stenosis, requiring ongoing treatment.  is reduced into the mild to moderate range.  EDITOR: Meg M. Sleeper, VMD, DACVIM
           •  In  cases  of  severe  obstruction  in  which   •  Restenosis occurs infrequently after balloon
             interventional or surgical treatment is not   valvuloplasty.





            Pulse Abnormalities                                                                    Client Education
                                                                                                          Sheet


            BASIC INFORMATION                  ASSOCIATED DISORDERS                 pulse amplitude alternates between a strong
                                               A detailed differential diagnosis is discussed   pulse and a weak or absent pulse)
           Definition                          on p. 1275.                        •  Variation in pulse rhythm: tachyarrhythmias
           The arterial pulse is produced by the fluctuation   •  Reduced pulse amplitude (hypokinetic pulse):   (atrial fibrillation, premature beats) or brady-
           between diastolic and systolic arterial pressure   decreased cardiac output or left ventricular   arrhythmias (second-degree atrioventricular
           and can be palpated as an impulse in superficial   outflow  tract  obstruction.  With  aortic  or   block)
           arteries, such as the femoral artery. Pulse deficit   subaortic stenosis, the pulse may be decreased   •  Regular  variation  in  pulse  amplitude:
           refers to a heartbeat that is heard on auscultation   and delayed (pulsus parvus et tardus).  exaggerated effect of respiration: pulsus
           or felt on the chest wall but does not generate   •  Increased  pulse  amplitude  (hyperkinetic   paradoxus (pericardial effusion with cardiac
           a palpable arterial pulse.           pulse): increased stroke volume or decreased   tamponade). The pulse is stronger during
                                                diastolic arterial pressure. Example: diastolic   expiration and weaker during inspiration.
           Synonyms                             runoff through a patent ductus arteriosus   •  Regional variation in pulse amplitude: arterial
           •  Hyperkinetic  pulse:  strong,  bounding,  or   causes a greater difference between systolic   thromboembolism (feline myocardial disease,
             water-hammer pulse                 and diastolic pressures (greater pulse   infective endocarditis, hypercoagulable
           •  Hypokinetic pulse: weak or thready pulse  pressure) and a correspondingly stronger     states)
                                                pulse.
           Epidemiology                        •  Pulse deficits (missing pulses compared with   Clinical Presentation
           SPECIES, AGE, SEX                    cardiac  auscultation):  tachyarrhythmias,   HISTORY, CHIEF COMPLAINT
           Dogs and cats of either sex and any age  severe myocardial failure (pulsus alternans;   Varies widely, depending on underlying cause

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