Page 1684 - Cote clinical veterinary advisor dogs and cats 4th
P. 1684

846   Pupil Abnormalities


           PHYSICAL EXAM FINDINGS               consisting of alternating tall-short QRS    PROGNOSIS & OUTCOME
           •  Systemic or primary cardiac problems may   complexes, that suggests pericardial effusion   Varies widely, depending on underlying cause
  VetBooks.ir  •  Femoral pulses are easiest to palpate in cats    DIAGNOSIS      PEARLS & CONSIDERATIONS
                                                and is unrelated to pulsus alternans.
            alter the pulse, and a complete physical exam
            is necessary.
            and dogs.
           •  The dorsal metatarsal pulse is also readily   Diagnostic Overview  Comments
            palpable.                         A pulse abnormality is a physical exam finding,   •  Palpation of the peripheral arterial pulse can
           •  Auscultate  heart  sounds  simultaneously   and its significance may vary from harmless   give useful information about stroke volume
            (by definition, a pulse deficit exists when a   (e.g., seemingly weak pulse in an obese patient)   and cardiac output.
            heart sound does not have a corresponding   to indicative of cardiac or systemic disturbances.   •  Palpation of the arterial pulse is not useful
            palpable peripheral pulse).       An intermittent pulse deficit should be investi-  for detecting systemic hypertension.
           •  Pulse quality relates mainly to pulse ampli-  gated initially with an electrocardiogram; a weak   •  Presence  of  a  hyperkinetic  pulse  may  be
            tude (also affected by rate of rise of arterial   pulse should be assessed with evaluation of the   more obvious than a diastolic murmur with
            pressure in systole and affected by pulse   patient’s intravascular volume status (hydration)   severe aortic insufficiency (as with infective
            duration).                        and cardiac function (auscultation, thoracic   endocarditis of the aortic valve).
                                              radiographs, echocardiogram).      •  Pulsus paradoxus is a very helpful finding
           Etiology and Pathophysiology                                            when cardiac tamponade is suspected, but
           •  Pulse  pressure:  difference  between  systolic   Differential Diagnosis  it may be difficult to detect if the dog is
            and diastolic blood pressure (BP)  •  Hypokinetic pulse: obesity, arterial disease/  panting.
            ○   Pulse pressure can be widened by an increase   disorder.  The  combination  of  hypokinetic
              in stroke volume or decreased diastolic BP   pulse and a palpably strong or hyperdynamic   Technician Tip
              (e.g., aortic insufficiency, patent ductus   heartbeat  (apex  beat)  strongly  suggests   Absent metatarsal pulses can be an indication
              arteriosus), increasing pulse amplitude.  outflow obstruction (e.g., moderate to   of hypotension.
           •  With premature beats, the weak ventricular   marked aortic stenosis; less commonly,
            contraction may not generate sufficient   pulmonic stenosis).        SUGGESTED READING
            systolic  pressure  to  open  the  aortic  valve,   •  Hyperkinetic pulse: thin body condition  Perloff JK: The arterial pulse. In Perloff JK: Physical
            and no S 2  or pulse is produced (S 1  is still   •  Variation  in  pulse  amplitude:  normal   examination  of  the  heart  and  circulation,  ed  4,
            normally heard).                    variation  as occurs with  respiratory sinus   Shelton, CT, 2009, People’s Medical Publishing
           •  Variations in stroke volume also occur with   arrhythmia (pulse is stronger after pause)  House, pp 55-91.
            the phase of respiration with cardiac tampon-
            ade, in which increased filling of the right   Initial Database      RELATED CLIENT EDUCATION
            heart during inspiration leads to decreased   •  Pulse deficits should prompt the recording   SHEET
            filling of the left heart and a reduced pulse   of an electrocardiogram (p. 1096).
            pressure.                         •  Alternate pulse deficits with normal sinus   Consent to Perform Echocardiography
           •  Pulsus alternans is an uncommon finding   rhythm (pulsus alternans): thoracic radio-
            characterized by alternate pulses that are very   graphs and an echocardiogram  AUTHOR: Virginia Luis Fuentes, VetMB, MA, PhD,
            weak or absent despite consistent electrical                         DVC, DACVIM, DECVIM
                                                                                 EDITOR: Leah A. Cohn, DVM, PhD, DACVIM
            activation (due to abnormal intracellular    TREATMENT
            calcium cycling in myocardial failure).
            It should not be confused with electrical   Treatment Overview
            alternans, an electrocardiographic finding   Manage the underlying cause.



            Pupil Abnormalities



            BASIC INFORMATION                 GENETICS, BREED PREDISPOSITION     HISTORY, CHIEF COMPLAINT
                                              •  Distorted  pupil:  a  distorted  pupil,  such   Abnormalities in pupil size and shape may be
           Definition                           as iris coloboma, may be breed related in   noted by the owner. Veterinarians may notice
           Abnormalities  include  pupils that  are inap-  dogs. Australian shepherds and Dalmatians   the pupil abnormalities during routine exams
           propriately dilated or constricted and those   are overrepresented.   or in animals presenting for painful, red, or
           with a distorted shape.            •  Dilated pupil                   blind eyes.
           •  Anisocoria: unequal or asymmetrical pupils  ○   Glaucoma, primary (predisposed breeds)
           •  Dyscoria: misshapen/distorted pupil  ○   Toy and miniature poodles are predisposed   PHYSICAL EXAM FINDINGS
           •  Miosis: constricted pupil           to optic nerve hypoplasia.     Dilated pupil and the following:
           •  Mydriasis: dilated pupil          ○   Heritable retinal degeneration in many   •  Scalloping at pupillary margin
                                                  breeds of dogs                   ○   Iris coloboma: focal; young animal
           Epidemiology                                                            ○   Iris atrophy: typically multifocal and/or
           SPECIES, AGE, SEX                  Clinical Presentation                  moth-eaten effect in iris stroma and/or
           •  Dogs and cats                   DISEASE FORMS/SUBTYPES                 at pupillary margin; typically age-related
           •  Iris  atrophy  is  an  aging  change  and  is   Conditions that lead to pupil abnormalities   change (i.e., older animals)
            therefore seen in older animals.  can be divided into those that cause  •  Blindness (negative menace response)
           •  Iris coloboma (absence of or defect in the   •  Pupillary dilation (mydriasis)  ○   See chapters on blindness, retinal degen-
            iris) is a developmental/heritable condition   •  Pupillary constriction (miosis)  eration, and retinal detachment (pp. 123,
            that is usually first noticed in young animals,   •  Abnormal pupil shape (dyscoria)  883, and 885).
            most frequently dogs.
                                                     www.ExpertConsult.com
   1679   1680   1681   1682   1683   1684   1685   1686   1687   1688   1689