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1404  Cardiopulmonary Cerebral Resuscitation



            Cardiopulmonary Cerebral Resuscitation
  VetBooks.ir                                     Unresponsive, apneic patient







                                                    Initiate CPR immediately

                                                      Basic life support
                                                    1 full cycle = 2 minutes
                                               uninterrupted compressions/ventilation
                                        1                                 2
                                Chest compressions                     Ventilation

                                                                          or

                                    100-120/min               10/min                 C:V 30:2
                                • Lateral recumbency  • Intubated in lateral recumbency  • Interpose compressions
                                • 1/2 to 2/3 chest width   • Simultaneous compressions
                                                     Advanced life support
                                        3                     4                    5
                                  Initiate monitoring                      Administer reversals
                           • Electrocardiogram (ECG)        Obtain      • Opioids – naloxone
                           • End-tidal CO  (EtCO )       vascular access  • Alpha-2 agonists – atipamezole
                                      2
                                           2
                               • >15 mm Hg = good compressions          • Benzodiazepines – flumazenil
                                                        Evaluate patient           Post-CPA
                                                          Check ECG       ROSC      algorithm




                                     VF/Pulseless VT                       Asystole/PEA


                          • Continue BLS, charge defibrillator  • Low-dose epinephrine and/or vasopressin
                          • Clear and give 1 shock                  every other BLS cycle
                              or Precordial thump if no defibrillator  • Consider atropine every other BLS cycle
                          • With prolonged VF/VT, consider      • With prolonged CPA > 10 min, consider
                              • Amiodarone or lidocaine             • High-dose epinephrine
                              • Epinephrine/vasopressin every other cycle      • Bicarbonate therapy
                              • Increase defibrillator dose by 50%




                                                       Basic life support
                                          Change compressor • Perform 1 full cycle = 2 minutes

                CPR algorithm chart. This chart summarizes the clinical guidelines most relevant to the patient presenting acutely in CPA. The box
                surrounded by the gray dashed line contains, in order, the initial BLS and ALS actions to be taken when a patient is diagnosed with
                CPA: (1) administration of chest compressions, (2) ventilation support, (3) initiation of ECG and EtCO  monitoring, (4) obtaining
                                                                                         2
                vascular access for drug administration, and (5) administration of reversal agents if any anesthetic/sedative agents have been
                administered. The algorithm then enters a loop of 2-minute cycles of CPR with brief pauses between to rotate compressors, to
                evaluate the patient for signs of ROSC, and to evaluate the ECG for a rhythm diagnosis. Patients in PEA or asystole should be
                treated with vasopressors and, potentially, anticholinergic drugs. These drugs should be administered no more often than every
                other cycle of CPR. Patients in VF or pulseless VT should be electrically defibrillated if a defibrillator is available, or mechanically
                defibrillated with a precordial thump if an electrical defibrillator is not available. Immediately after defibrillation, another 2-minute
                cycle of BLS should be started. The defibrillator dose can be increased by 50% after the first shock if a second shock is necessary.
                ALS, Advanced  life  support;  BLS,  basic  life  support;  CPA,  cardiopulmonary  arrest;  CPR,  cardiopulmomary  resuscitation;  C:V,
                compression-to-ventilation ratio; EtCO , end-tidal CO ; PEA, pulseless electrical activity; ROSC, return of spontaneous circulation;
                                           2
                                                     2
                VF, ventricular fibrillation; VT, ventricular tachycardia.
                (Modified from Fletcher DJ, et al: RECOVER evidence and knowledge gap analysis on veterinary CPR. Part 7: Clinical guidelines. J Vet Emerg Crit Care.
                22(S1):S102–S131, 2012.)
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