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Cardiopulmonary Cerebral Resuscitation Post-Arrest Care   1405



            Cardiopulmonary Cerebral Resuscitation Post-Arrest Care
  VetBooks.ir                                              ROSC



                                      RESPIRATORY    Spontaneous breathing?  NO
                                                     Spontaneous breathing?
                                      OPTIMIZATION
                                                               YES
                                                                                IPPV
                                                                                IPPV
                                                    PaCO  or EtCO +5 mm Hg or EtCO + 5 mm Hg
                                                    PaCO  2 2  2 2
                                                      Dog = 32-43 mm Hg?Dog = 32-43 mm Hg?
                                                      Cat = 26-36 mm Hg?Cat = 26-36 mm Hg?  NO
                                                                                   YES
                                                               YES
                                                                          NO
                                                                              FiO2   0.6
                                                    Titrate supplemental oxygen
                                                    Titrate supplemental oxygen  FiO 2  ≥ 0.6
                                                           2
                                         SpO 2  > 98%   SpO  = 94%-98%    SpO  < 94%
                                                                             2
                                       PaO  > 100 mm Hg PaO  = 80-100 mm Hg  PaO  < 80 mm Hg
                                          2
                                                                           2
                                                         2
                                         Hyperoxemic      Normoxemic      Hypoxemic
                                      SAP > 200 mm Hg  SAP = 100-200 mm Hg  SAP < 100 mm Hg
                                      MAP > 120 mm Hg  MAP = 80-120 mm Hg  MAP < 80 mm Hg
                                        Hypertensive     Normotensive     Hypotensive

                                                                70%
                                             1 1        SCVO ≥ ≥ 70%  NO      1 1
                                                             2
                                                        SCVO 2
                                                                          Hypovolemia?
                                          ↓ Pressor      Lactate < 2.5    Hypovolemia?
                                          ↓ Pressor
                                                         Lactate < 2.5
                                                                            < 10 mm H
                                                                        CVP
                                                                                    O?
                                                          mmol/L?       CVP < 10 mm H O?
                                                          mmol/L?
                                                                                   2 2
                                             2 2
                                          Treat pain  YES                         YES
                                          Treat pain
                                                                               IV fluids
                                             3 3                               IV fluids
                                            Anti-
                                            Anti-
                                         hypertensive                          2  2
                                         hypertensive
                                                                           Vasodilation?
                                                                           Vasodilation?
                                                                        ↓ CRT, Injected MM?
                                                                        ↓ CRT, Injected MM?
                                                                                  YES
                                                                              Vasopressor
                                                                              Vasopressor
                                                             4 4                3 3
                                                         PCV < 25%?
                                                         PCV < 25%?        ↓ Contractility?
                                                                           ↓ Contractility?
                                                               YES                YES
                                                                              + Inotrope
                                                          Transfuse
                                                          T ransfuse          + Inotrope
                                   HEMODYNAMIC
                                    OPTIMIZATION
                                                                                                                      Clinical   Algorithms
                                               NEUROPROTECTION
                                               NEUROPROTECTION
                                                   ICU
                                                   ICU
                                                 Consider:
                                                 Consider:
                                          • Hypothermia if comatose
                                          • Mannitol/HTS if neuro signs
                                          • Seizure prophylaxis
                Post-cardiac arrest (PCA) care algorithm. This chart summarizes a comprehensive treatment protocol for PCA care that includes
                components of controlled ventilation and oxygenation, goal-directed hemodynamic optimization, and neuroprotective strategies.
                The sequence shown reflects the order in which each component should be assessed and treatment initiated. Assessment and
                initiation of treatment for the subsequent component will likely commence before the endpoints of the previous component have
                been completely met. Thus respiratory, hemodynamic, and neuroprotective treatment strategies will be initiated in parallel in most
                cases.
                CRT, Capillary refill time; CVP, central venous pressure; EtCO , end-tidal carbon dioxide; HTS, hypertonic saline; ICU, intensive
                                                             2
                care unit; IPPV, intermittent positive pressure ventilation; MAP, mean arterial pressure; MM, mucous membrane color; PaO 2 , partial
                pressure of oxygen, arterial; PCV, packed cell volume; ROSC, return of spontaneous circulation; SAP, systolic arterial pressure;
                SCVO , central venous oxygen saturation; SpO 2 , peripheral capillary oxygen saturation.
                     2
                (From Fletcher DJ, et al: RECOVER evidence and knowledge gap analysis on veterinary CPR. Part 7: Clinical guidelines. J Vet Emerg Crit Care. 22(S1):S102–S131, 2012.)
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