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1412 Disseminated Intravascular Coagulation

Disseminated Intravascular Coagulation
VetBooks.ir

Suspect disseminated intravascular
coagulation (DIC)

Diagnose and treat
primary condition

Evaluate coagulation: Maintain adequate
hypocoagulable? tissue perfusion
(increased prothrombin
time, activated partial
thromboplastin time)
No Yes As indicated:
• Blood transfusion
• Oxygen supplementation
Heparin (consider unfractionated): • Fresh-frozen plasma • Antibiotics
• 100-200 IU/kg subcutaneous q 8h, or transfusion (10-15 mL/kg • Other specific therapies
Low–molecular-weight heparin: IV) q 12h aimed at primary condition
• Dalteparin (Fragmin) 100-200 IU/kg subcutaneous • Fresh whole blood
q 8-12h, or 15-25 U/kg/h IV constant rate infusion, OR transfusion if PCV < 20%
• Enoxaparin (Lovenox) 1-1.5 mg/kg subcutaneous
q 12h

UPDATED AND EDITED BY: Leah A. Cohn, DVM, PhD, DACVIM
ORIGINALLY WRITTEN BY: Scott P. Shaw, DVM, DACVECC

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