Page 2758 - Cote clinical veterinary advisor dogs and cats 4th

1436 Mast Cell Tumor, Dog

Mast Cell Tumor, Dog
VetBooks.ir Is tumor surgically resectable?

Yes No

• Is tumor located on • Complete staging
prepuce, scrotum, indicated to formulate
digit, or head? treatment plan
or • Consider chemotherapy
• Is tumor recurrent? tyrosine kinase
or Yes • Complete staging indicated to inhibitor radiotherapy
• Is peritumoral edema formulate treatment plan (radiotherapy for
or bruising present? • Distant metastasis detected? palliation of local
disease)
No
No Yes
• Perform lymph node Yes
aspirate and blood work No
• Lymph node Regional lymph node Consider chemotherapy
metastasis present? metastasis detected? tyrosine kinase inhibitor
radiotherapy (radiotherapy
No Yes for palliation of local disease)

Surgically excise tumor for grade and margins If resectable, remove
lymph node(s) and
Histologic grade primary tumor for
grade and margins
Poorly
differentiated MCT
Well- or
immediately • Complete staging indicated;
differentiated chemotherapy tyrosine
MCT kinase inhibitor radiotherapy
if incompletely excised
• Monitor regularly for MCT
recurrence and metastasis
Determine
completeness
of excision
Complete Incomplete excision
excision
• Monitor regularly for MCT Consider scar revision
recurrence and metastasis or radiotherapy to treat
• Chemotherapy and/or microscopic disease
tyrosine kinase inhibitor
are indicated if lymph node
metastasis was present at
diagnosis or for tumors
located in sites associated
with increased metastasis
MCT, Mast cell tumor.

EDITED BY: Leah A. Cohn, DVM, PhD, DACVIM
ORIGINALLY WRITTEN BY: Tracy Gieger, DVM, DACVIM, DACVR

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