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Nodular Dermatosis 1437.e3

Nodular dermatitis: advanced workup
VetBooks.ir

Microbial culture ± sensitivity: Serologic testing Additional testing on
• Specimen: skin biopsy for tissue maceration Latex agglutination biopsied samples:
and culture antigen detection: • Direct immunofluorescence
• Obtain specimen with aseptic techniques • Cryptococcosis • Immunoperoxidase staining
• Inform laboratories of suspected agent(s) for: Antibody response: • Immunohistochemistry
Appropriate transport and culture media selection • Coccidioidomycosis • Immunostaining with
Potential extended culture time • Blastomycosis polyclonal BCG antibody
Handling of zoonotic agents with care (less reliable) • Polymerase chain reaction
• Leishmaniasis

Fungal culture Additional laboratory tests:
Dermatophytes: • FeLV/FIV
• Microsporum canis • ANA
• M. gypseum • CBC
• Trichophyton mentagrophytes • Serum biochemistry profile
Subcutaneous mycoses: • Urinalysis
• Sporotrichosis
• Pythiosis
• Phaeohyphomycosis
• Zygomycosis
• Pseudomycetoma/mycetoma
Deep/systemic mycoses:
• Blastomycosis
• Coccidioidomycosis
• Histoplasmosis Diagnostic imaging:
• Cryptococcosis • Assess local invasion into body tissue
Algae: • Dissemination of infectious etiology (chest, abdomen)
• Protothecosis • Metastasis check of neoplastic conditions

Bacterial cultures
Aerobic:
• Staphylococcus spp.
• Pseudomonas spp.
• Proteus spp.
• Rhodococcus equi
• Nocardia spp.
Anaerobic:
• Actinomyces spp.
Mycobacterial:
• Mycobacterium chelonei
• M. fortuitum
• M. smegmatis
• M. phlei ANA, Antinuclear antibodies; BCG, bacillus Calmette-Guérin
• M. xenopi antibody; CBC, complete blood count; FeLV, feline leukemia
• M. thermoresistible virus; FIV, feline immunodeficiency virus.

EDITED BY: Leah A. Cohn, DVM, PhD, DACVIM
ORIGINALLY WRITTEN BY: Anthony Yu, DVM, DACVD
Clinical Algorithms

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