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CHAPTER 5   Congenital Cardiac Disease   117


            consists of frequent small, semisolid, or liquid meals eaten   OTHER VASCULAR ANOMALIES
            in an upright position. This feeding method may be neces-  A number of venous anomalies have been described, but
  VetBooks.ir  sary indefinitely. Persistent regurgitation occurs in some   most are not clinically relevant. The persistent left cranial
                                                                 vena cava is a fetal venous remnant that courses lateral to the
            dogs despite successful surgery, suggesting a permanent
                                                                 left AV groove and empties into the coronary sinus of the
            esophageal motility disorder.
                                                                 caudal RA. Although it causes no clinical signs, its presence
            COR TRIATRIATUM                                      may complicate surgical exposure of other structures at the
            Cor triatriatum is an uncommon malformation caused by an   left heart base. Portosystemic venous shunts are common
            abnormal membrane that divides either the right (dexter) or   and can lead to hepatic encephalopathy, as well as other
            the left (sinister) atrium into two chambers. Cor triatriatum   signs. These malformations are thought to be more prevalent
            dexter occurs sporadically in dogs, often in combination   in  the  Yorkshire  Terrier,  Pug,  Miniature  and  Standard
            with PS. Cor triatriatum sinister has been described rarely   Schnauzers, Maltese, Pekingese, Shih Tzu, and Lhasa Apso
            in cats; functional consequences are similar to mitral valve   breeds and are discussed in Chapter 38.
            stenosis.
              Cor triatriatum dexter results from failure of the embry-  Suggested Readings
            onic right sinus venosus valve to regress. The caudal vena   General References
            cava and coronary sinus empty into the RA caudal to the   Beijerink NJ, Oyama MA, Bonagura JD. Congenital heart disease.
            intra-atrial membrane; the tricuspid orifice is within the   In: Ettinger SJ, Feldman EC, Cote E, eds. Textbook of veterinary
            cranial RA “chamber.” Obstruction to venous flow through   internal medicine. 8th ed. St Louis: Elsevier; 2017:1207–1248.
            the  opening  in  the  abnormal  membrane  elevates  vascular   Buchanan JW. Prevalence of cardiovascular disorders. In: Fox PR,
            pressure in the caudal vena cava and the structures that drain   Sisson D, Moise NS, eds. Textbook of canine and feline cardiology.
            into it.                                              2nd ed. Philadelphia: Saunders; 1999:457.
              Large- to medium-size breeds of dog are most often   Oliveira P, et al. Retrospective review of congenital heart disease in
            affected. Persistent ascites that develops at an early age is the   976 dogs. J Vet Intern Med. 2011;25:477–483.
            most prominent clinical sign. Exercise intolerance, lethargy,   Schrope DP. Prevalence of congenital heart disease in 76,301 mixed
                                                                  breed dogs and 57,025 mixed-breed cats. J Vet Cardiol. 2015;17:
            distended cutaneous abdominal veins, and sometimes diar-  192–202.
            rhea are reported as well. Neither a cardiac murmur nor   Tidholm A, et al. Congenital heart defects in cats: a retrospective
            jugular venous distention is a feature of this anomaly.  study of 162 cats (1996-2013).  J Vet Cardiol. 2015;17(suppl
              Thoracic radiographs indicate caudal vena cava distention   1):S215–S219.
            without generalized cardiomegaly. The diaphragm may be   Ventricular Outflow Obstruction
            displaced cranially by massive ascites. The ECG usually is   Buchanan JW. Pathogenesis of single right coronary artery and
            normal. Echocardiography reveals the abnormal membrane   pulmonic stenosis in English bulldogs. J Vet Intern Med. 2001;15:
            and prominence of the caudal RA chamber and vena cava.   101–104.
            Doppler studies show the flow disturbance within the RA   Bussadori C, et al. Balloon valvuloplasty in 30 dogs with pulmonic
            and allow estimation of the intra-RA transmembrane pres-  stenosis: effect of valve morphology and annular size on initial
            sure gradient.                                        and 1-year outcome. J Vet Intern Med. 2001;15:553–558.
              Successful  therapy  requires  enlarging  the  membrane   Estrada A, et al. Prospective evaluation of the balloon-to-annulus
            orifice or excising the abnormal membrane to remove flow   ratio for valvuloplasty in the treatment of pulmonic stenosis in
            obstruction. A minimally invasive option is percutaneous   the dog. J Vet Intern Med. 2006;20:862–872.
            balloon dilation of the membrane orifice. A small cutting   Fonfara S, et al. Balloon valvuloplasty for treatment of pulmonic
                                                                  stenosis in English Bulldogs with aberrant coronary artery. J Vet
            balloon can be used to score the orifice opening before dila-  Intern Med. 2010;24:354–359.
            tion with a larger balloon. Alternatively, a surgical approach   Francis AJ, et al. Outcome in 55 dog with pulmonic stenosis that
            using inflow occlusion, with or without hypothermia, can be   did not undergo balloon valvuloplasty or surgery. J Small Anim
            used to excise the membrane or break it down using a valve   Prac. 2011;52:282–288.
            dilator.                                             Kienle RD, Thomas WP, Pion PD. The natural history of canine
                                                                  congenital subaortic stenosis. J Vet Intern Med. 1994;8:423–431.
            ENDOCARDIAL FIBROELASTOSIS                           Kleman ME, et al. How to perform combined cutting balloon and
            Diffuse fibroelastic thickening of the LV and LA endocar-  high-pressure balloon valvuloplasty for dogs with subaortic ste-
            dium, with dilation of the affected chambers, characterizes   nosis. J Vet Cardiol. 2012;14:351–361.
            endocardial fibroelastosis. This congenital abnormality has   Koplitz SL, et al. Aortic ejection velocity in healthy Boxers with soft
            been reported occasionally in cats, especially Burmese and   cardiac murmurs and Boxers without cardiac murmurs: 201
                                                                  cases (1997-2001). J Am Vet Med Assoc. 2003;222:770–774.
            Siamese. Left-sided or biventricular heart failure commonly   Locatelli C, et al. Independent predictors of immediate and long-
            develops early in life. A mitral regurgitation murmur may be   term results after pulmonary balloon valvuloplasty in dogs. J Vet
            present.  Criteria for  LV and LA enlargement are seen on   Cardiol. 2011;13:21–30.
            radiographs, ECG, and echocardiogram. Evidence for   Meurs KM, Lehmkuhl LB, Bonagura JD. Survival times in dogs
            reduced LV myocardial function may be present. Definitive   with severe subvalvular aortic stenosis treated with balloon val-
            antemortem diagnosis is difficult.                    vuloplasty or atenolol. J Am Vet Med Assoc. 2005;227:420–424.
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