Page 408 - Small Animal Internal Medicine, 6th Edition
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380    PART II   Respiratory System Disorders



                   TABLE 25.1
  VetBooks.ir  Drugs Used to Decrease Stress in Animals With Respiratory Distress


             Upper Airway Obstruction: Decreases Anxiety and Lessens Respiratory Efforts, Decreasing Negative Pressure Within
             Upper Airways
             Acepromazine      Dogs and cats          0.01-0.2 mg/kg IV, IM, SC (no more than 3 mg total dose)
             Morphine          Dogs only, particularly   0.2-2.0 mg/kg IM, SC; CRI, 0.1-0.3 mg/kg loading dose, then
                                 brachycephalic dogs    0.1-0.3 mg/kg/h
             Pulmonary Edema: Decreases Anxiety
             Morphine          Dogs only              0.2-2.0 mg/kg IM, SC; CRI, 0.1-0.3 mg/kg loading dose, then
                                                        0.1-0.3 mg/kg/h
             Acepromazine      Dogs and cats          0.01-0.2 mg/kg IV, IM, SC (no more than 3 mg total dose)

             Rib Fractures, After Thoracotomy, Other Trauma: Pain Relief
             Hydromorphone     Dogs and cats          0.1-0.2 mg/kg IV, IM, SC; CRI, 0.025-0.050 mg/kg IV loading dose,
                                                        then 0.01-0.04 mg/kg/h
             Butorphanol       Dogs and cats          0.1-0.8 mg/kg IV, IM, SC; CRI, 0.1-0.2 mg/kg IV loading dose, then
                                                        0.1-0.2 mg/kg/h
             Buprenorphine     Dogs and cats          0.005-0.020 mg/kg IV, IM

            CRI, Continuous-rate infusion; IM, intramuscularly; IV, intravenously; SC, subcutaneously.
            Dosage recommendations from Quandt J: Analgesia, anesthesia, and chemical restraint in the emergent small animal patient, Vet Clin North
            Am Small Anim Pract 43:214, 2013.


                   TABLE 25.2
            Localization of Respiratory Tract Disease by Physical Examination Findings in Dogs and Cats With Severe
            Respiratory Distress
                             LARGE AIRWAY DISEASE            PULMONARY PARENCHYMAL DISEASE
                                                                                     OBSTRUCTIVE
                        EXTRATHORACIC                                                AND           PLEURAL
                        (UPPER)          INTRATHORACIC   OBSTRUCTIVE     RESTRICTIVE  RESTRICTIVE  SPACE DISEASE
             Respiratory   Nl-↑          Nl-↑            ↑↑↑             ↑↑↑         ↑↑↑           ↑↑↑
               rate
             Relative   ↑↑↑Inspiration   ↑↑Expiration    ↑Expiration     ↑↑Inspiration  No difference  ↑Inspiration
               effort
             Audible    Inpiratory stridor,   Expiratory    Rarely expiratory   None  None         None
               sounds     stertor         cough/wheeze     wheeze
             Auscultable   Referred upper   End expiratory   Expiratory   ↑↑Breath   ↑↑Breath      ↓Breath sounds
               sounds     airway sounds;   click; ↑↑breath   wheezes or   sounds;      sounds,
                          ↑↑breath        sounds           ↑↑breath       ±crackles    crackles,
                          sounds                           sounds; rarely,             and/or
                                                           ↓breath                     wheezes
                                                           sounds with
                                                           air trapping

            ↑, Slightly increased; ↑↑, increased; ↑↑↑, markedly increased; ↓, decreased; Nl, normal. Normal respiratory rates for dogs and cats at rest
            are ≤ 20/min. In the hospital setting, rates of ≤ 30/min are generally accepted as normal.


            be increased (i.e., deep breaths are taken). Breath sounds are   inspiration, which is generally prolonged relative to expira-
            often increased.                                     tion. Stridor or stertor is usually heard, generally during
                                                                 inspiration. A history of voice change may be present with
            Extrathoracic (Upper) Airway Obstruction             laryngeal disease.
            Patients with extrathoracic (upper) airway obstruc-    Laryngeal paralysis and brachycephalic airway syndrome
            tion typically exhibit the greatest breathing effort during   are the most common causes of upper airway obstruction
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