Page 886 - Problem-Based Feline Medicine
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878   PART 10  CAT WITH SIGNS OF NEUROLOGICAL DISEASE


          upon culture and sensitivity results. Amoxicillin/clavu-  Pathogenesis
          lanic acid (14 mg/kg PO q 12 h) in combination is a rea-
                                                        Many, if not all, of these cats are positive for the feline
          sonable antibiotic to begin treatment with prior to
                                                        leukemia virus.
          receiving culture and sensitivity results.
                                                        A C-type RNA virus has been demonstrated in the
          Antifungal drugs may be used locally or systemically
                                                        short ciliary nerves and ganglion of some cats.
          depending upon the offending organism (see section on
          antifungal therapy).                          Additionally, feline immunodeficiency virus may play
                                                        an associated role.
          Foreign bodies should be removed with forceps or a sim-
          ilar instrument or during surgery.
                                                        Clinical signs
          Surgical drainage (bulla osteotomy) is often needed
          for curative treatment.                       The pupils are usually fixed at a midrange size and
                                                        do not dilate appropriately with dark adaptation.
          Prognosis                                     The pupil diameters may alternate in size between eyes,
                                                        and pupil movement is abnormal. There is inability to
          The prognosis for treatment of middle ear disease with
                                                        fully dilate in the dark and sluggish constriction to light
          either appropriate antimicrobials or surgery is usually
                                                        stimulation.
          good.
          Surgery of the bulla may result in complications such
                                                        Diagnosis
          as a head tilt and facial nerve paralysis which may be
          persistent.                                   The diagnosis is suspected in a cat with the appropriate
                                                        clinical signs that is also FeLV positive.
          Prevention
                                                        Differential diagnosis
          Early appropriate treatment of otitis externa may be
          helpful in preventing extension to the middle ear.  Rule out primary iris movement problems such as
                                                        synechia.
          Correcting anatomical defects of the ear canal
          decreases the risk of otitis.
                                                        Treatment
          Decrease or stop activities that predispose to water or
          foreign material collecting in the ear.       There is no specific treatment for this disease.

          SPASTIC PUPIL SYNDROME**                      Prognosis
                                                        The prognosis for the pupillary abnormality is variable.
           Classical signs
                                                        The overall prognosis will be determined by other asso-
           ● Pupils are usually fixed at a midrange size  ciated FeLV-related neoplastic conditions that may
             and do not dilate appropriately with dark  arise.
             adaptation.
           ● Pupil diameters may alternate in size
             between eyes.                              Prevention
           ● Pupil movement is abnormal (inability to   Decrease exposure to other FeLV-positive cats.
             fully dilate in the dark; sluggish
             constriction to light stimulation).        Vaccination of FeLV infection may provide some pre-
                                                        vention.
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