Page 973 - Adams and Stashak's Lameness in Horses, 7th Edition
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Principles of Therapy for Lameness  939


               diathermy units operate at a frequency higher than that   accelerate tissue healing by improving fibroblast function,
             used for shortwave diathermy. Heating occurs by pro-  enhancing local microcirculation and oxygen supply, aiding
  VetBooks.ir  the tissues, creating vibrational energy that results in   cularization, and promoting angiogenesis.  In addition,
                                                                 in the removal of waste products,  increasing neovas-
             duction of electromagnetic radiation that is absorbed in
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             heat production. Tissues with high water content absorb
                                                                 laser therapy significantly reduces inflammation by decreas-
             microwaves strongly with muscle and joint effusion   ing the production of prostaglandins, TNF‐alpha, IL‐1beta,
             heated preferentially.  The tissue effects are determined   plasminogen activator, and cyclooxygenase.  Laser therapy
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             by the degree of tissue heating that occurs, similar to   has also been demonstrated to improve motor and sensory
             that described for therapeutic ultrasound above.    nerve conduction by enhancing myelin production, 123,195  as
                                                                 well as improving collagen fiber alignment within injured
             Evidence in Humans                                  tendons. 87
                                                                   There is also evidence that laser therapy may improve
               Radiofrequency diathermy has been shown to signifi-  muscle strength and recovery in human athletes. LLLT
             cantly improve shoulder pain, range of motion, and bet-  applied to people before an eccentric training session
             ter performance in activities of daily living in people   improved muscular strength gain and the hypertrophic
             with frozen shoulder.  In addition, radiofrequency dia-  muscle  response.   LLLT  performed  in  elderly  women
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             thermy had a small but significant effect on pain and   resulted in increased number of knee flexion–extension
             muscle performance in patients with knee osteoarthri-  repetitions compared with those who received sham
             tis.  However, another study demonstrated no addi-  treatment.  In a study of university athletes with a vari-
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             tional benefit of radiofrequency diathermy for knee   ety of musculoskeletal injuries, those who received LLLT
             osteoarthritis when isokinetic exercises were performed.    had a significantly shorter return‐to‐play duration than
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             This modality must be used with caution, as negative   those who did not receive laser therapy. 54
             effects, such as burns/scalding at the application site and   HILT may be more effective than LLLT for certain
             teratogenic effects in pregnant animal species have been   conditions. HILT is able to reach and stimulate large
             described. Radiofrequency diathermy is contraindicated   and/or deep structures that are difficult to reach with
             in humans with metal implants (excessive heating can   LLLT. In a study comparing HILT versus LLLT for
             occur) and those with a cardiac pacemaker. 35       patients with knee osteoarthritis, HILT was more effec-
                                                                 tive than LLLT at reducing pain after 6 weeks of treat-
             Evidence in Horses                                  ment.  HILT was also shown to significantly increase
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                                                                 range of motion, decrease pain, and improve functional
               Currently, no studies are available in the horse.
                                                                 disability in patients with cervical and shoulder pain. 5,153
                                                                 For patients with chronic low back pain, HILT com-
             Laser Therapy                                       bined with exercise was more effective at reducing pain
                                                                 and improving function than exercise and HILT alone. 4
             Mechanism of Action
               Light amplification by stimulated emission of radia-
             tion (laser) is created when energy from a power source   Evidence in Horses
             excites a lasing medium. Energy is then released as pho-  Laser therapy in horses has not been as extensively
             tons. The laser medium typically creates light with one   researched. However, studies show that equine patient
             wavelength (monochromatic). Biostimulating lasers are   preparation is essential to having adequate laser energy
             those used in our rehabilitation patients and are catego-  penetration. Clipping and cleaning of the limb results in
             rized into classes 1–4. 79,166  Class 1 and 2 lasers have no   significantly greater energy penetration than in unclipped
             adverse effects on eyes and skin (laser pointers, laser   limbs. 43,168  In horses with unclipped hair, only white or
             used for laser disc). Class 3 lasers are those used for low‐  cream‐colored hair allowed laser energy to penetrate
             level laser therapy (LLLT) that operate at a power level   through equine skin. In horses with gray, brown, chest-
             <500  mW and include mid‐power lasers that are safe on   nut, and black hair, >99% of laser energy is blocked if
             the skin but carry a risk for eye injury (cold lasers used   unclipped. Better penetration occurs in all horses after
             for therapeutic purposes).  Class 3 lasers are further   clipping; however, energy penetration is still greatest in
                                    17
             subcategorized into Class 3a and 3b. Class 3a lasers   nonpigmented skin and is greater for medium‐colored
             consist  of  lasers  from  1  to  5 mW  in  power  and  pose   than dark‐colored skin. While a longer wavelength is
             moderate ocular hazard. Class 3b lasers consist of lasers   meant to result in greater energy penetration, skin color
             from 5 to 500 mW power output and pose greater ocu-  has been shown to have a greater effect. In horses with
             lar hazard than Class 3a.  Class 4 lasers are used for   moderate/dark pigmented skin, laser energy penetration
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             high‐intensity laser therapy (HILT) and carry a risk to   was greater at a wavelength of 980  nm compared with
             both eyes and skin (used for therapeutic purposes). 17,79    800  nm. However, in horses with nonpigmented skin,
             The effect that occurs in the tissue depends on the wave-  energy penetration was greater  at 800  nm than at
             length and power that is used, as well as the absorption   980 nm.   Therefore, adjusting laser setting based on
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             potential of the tissue itself. 17                  skin pigmentation is critical if targeting deeper tissues.
                                                                   One retrospective equine study is available showing
                                                                 the benefit of laser therapy in horses with tendinopathy/
             Evidence in Humans and Laboratory Animals
                                                                 desmopathy. In a study of 150 sport horses with tendi-
               Both LLLT and HILT have been shown to reduce mus-  nopathy/desmopathy  of  the  SDFT,  deep  digital  flexor
             culoskeletal pain, increase range of motion, and reduce   tendon (DDFT), and suspensory ligament (SL), lame-
             neuropathic pain. 1,48,186  Laser therapy has been shown to   ness, and ultrasound scores were significantly improved
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