Page 429 - Anatomy and Physiology of Farm Animals, 8th Edition
P. 429

414 / Anatomy and Physiology of Farm Animals

          Nutrition                               nutrient, nitrogen balance is often used as
                                                  an indicator of the status of protein metab-
  VetBooks.ir  The nutritional needs of animals vary   olism. If an animal consumes more nitro-

                                                  gen than it excretes, it is said to be in a
          greatly with their metabolic state. A rapidly
          growing, active young animal has much   positive nitrogen balance, indicating that
          different nutritional needs from those of   the animal is synthesizing more body pro-
          an older, more sedentary animal. Both ani-  teins than are being degraded and lost
          mals must consume certain  essential    from the body. Young, growing animals are
          nutrients (compounds needed for normal   typically in positive nitrogen balance.
          growth and/or survival that cannot be syn-  During prolonged starvation, an animal is
          thesized in adequate amounts in the body),   in negative nitrogen balance, for body pro-
          but the amounts of these nutrients per unit   teins are broken down to provide energy,
          of body weight and the relative amounts of   and the resulting nitrogen is  excreted in
          specific nutrients vary.                the urine.
            Some essential nutrients are required in
          minute quantities and are toxic in large
          quantities. For example, copper is an essen-  Metabolism
          tial mineral, but excessive consumption
          over a short period leads to copper toxicity.   The terms anabolic and catabolic are used
          Minerals that are needed in small quanti-  to  describe  the  overall  metabolic  state  or
          ties are often termed  trace minerals.   status of an animal. Anabolism refers to a
          Vitamins function as coenzymes for vari-  constructive process (e.g., synthesis of pro-
          ous biochemical reactions throughout the   teins  from  amino  acids),  while catabolism
          body and are also typically required in small   refers to a destructive process (e.g., degra-
          amounts. Water‐soluble vitamins (B com-  dation of proteins into individual amino
          plex, biotin, C, folic acid, and niacin) are   acids). While anabolic and catabolic refer to
          not stored in the body, but fat‐soluble vita-  the overall metabolic status, both processes
          mins (A, D, E, and K) are stored in the liver   are usually ongoing at the same time in an
          and adipose tissue. Water‐soluble vitamins   animal’s body. For example, even in a young,
          can be consumed in large amounts without   rapidly growing animal that is digesting a
          significant toxicities because the excess is   meal, absorbing nutrients, and synthesizing
          rapidly excreted in the urine, whereas   body proteins, some body proteins are
          excessive consumption of fat‐soluble vita-  degrading at the same time. However, in
          mins can be harmful. Some rodenticides   this case, the rate of protein synthesis is
          (poisons that are used to kill mice and   greater than the rate of protein degradation,
          rats) contain excess levels of vitamin D,   so the animal is in an anabolic state.
          which results in increased calcium         Several hormones contribute to the reg-
          absorption, leading to acute renal fail-  ulation of the balance between anabolic
          ure, and death of the animal. Accidental   and catabolic processes, and the study of
          poisoning of nontarget species, includ-  the hormones that regulate metabolism is
          ing dogs, cats and children, can occur if   termed metabolic endocrinology. A com-
          the  rodenticide is  consumed in  toxic   mon feature of such hormones is that
          quantities.                             blood glucose concentrations participate
            The nutritional and metabolic status of   in regulation of their secretion. This indi-
          individual animals may be evaluated by   cates that the maintenance of a minimal
          determining the balance for a given nutri-  and constant source of glucose for energy
          ent or type of nutrient. Balance is deter-  is a key factor in the overall endocrine con-
          mined by comparing the amount consumed   trol of metabolism.
          by the animal to the amount used or lost   To study the endocrine control of anab-
          from the body. For example, because pro-  olism and catabolism, metabolic endocri-
          teins are the primary nitrogen‐containing   nologists often contrast the period shortly
   424   425   426   427   428   429   430   431   432   433   434