Page 43 - Anatomy and Physiology of Farm Animals, 8th Edition
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                                                                    H
                                                      CH 3
  VetBooks.ir                                  CH 3   C      CH 2   C
                                                 H

                                           CH 2    CH     CH 2  CH 2    CH 3
                                                                    CH 3
                                               C       CH 2
                                       CH 2
                                   CH 3
                               CH 2    CH      CH      CH 2
                                   C
                           CH 2            CH
                           CH              CH 2
                      HO           C
                               CH 2    CH
          Figure 2-5.  Cholesterol. Different biologic steroids are formed by modifying the cholesterol molecule,
          but the four carbon rings remain intact.



          of the steroids found in animals are derived   lactose, or milk sugar (glucose + galactose);
          from cholesterol (e.g., bile salts and various   and maltose (glucose + glucose).
          hormones, including several reproductive   Multiple molecules of glucose can be
          hormones). Cholesterol itself is an essen­  linked (polymerized) to form a polysaccha­
          tial constituent of the cell membrane of all   ride, glycogen. Two major sites of glycogen
          animal cells. Cholesterol can be obtained   synthesis are the liver and skeletal muscle.
          from  dietary  sources,  but  it  is  also   In the liver, the stored glycogen can be
          synthesized in the liver of animals,    broken down to glucose and metabolized
          including humans. Inappropriate rates   by liver cells or secreted as glucose into the
          of cholesterol synthesis by the liver are   blood. In skeletal muscle, glycogen stores
          responsible for elevation in serum cho-  are an immediate source of energy, but this
          lesterol in humans in spite of reductions   glycogen cannot be a source of glucose for
          in dietary intake of cholesterol.       release into the blood.
            Waxes are a class of lipids. The waxes   Glucose is a source of cell energy, and
          synthesized in the animal occur mostly in   the enzymatic pathway that metabolizes
          the epithelial cells of the skin. Here the   glucose to produce energy is  glycolysis.
          waxes form a protective coating on the   This pathway can be completed within the
          skin or hair as a water repellent and as a   cytosol, resulting in the production of ATP
          barrier against bacteria. Lanolin is wool   and pyruvate. If oxygen is readily available,
          fat, and cerumen is earwax.             the pyruvate can enter the mitochondria to
                                                  be metabolized.
                                                     The sugar deoxyribose is found in com­
          Carbohydrates                           bination with a base (purine or pyrimidine)
                                                  and a phosphate, forming DNA (deoxyri-
          Like lipids, carbohydrates are composed of   bonucleic acid). DNA is the carrier of all
          carbon, oxygen, and hydrogen. Simple    genetic information from generation to
          sugars, or monosaccharides, are carbohy­  generation, and from cell to cell, and ulti­
          drates containing three to seven carbon   mately controls all functions of the cell.
          atoms. Glucose, with six carbon atoms, is   DNA is found almost exclusively in the
          the most prevalent simple sugar in the   nucleus of the cell. A related substance,
          body. Two simple sugar molecules may be   RNA (ribonucleic  acid), includes the
          combined  to  form  a  disaccharide.  Some   sugar ribose combined with a base and a
          common and important disaccharides are:   phosphate. RNA is transcribed from DNA
          sucrose, or table sugar (glucose + fructose);   within the nucleus of the cell and eventually
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