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27  Feline Myocardial Disease  271


  VetBooks.ir                                 Cat with tachypnea/suspected acute CHF


                                                           O , (sedation?)
                                                            2
                              ?Absent breath
                             sounds ventrally              Auscultation


                                          Gallop or      Normal or murmur
                                          Arrhythmia

                  Thoracocentesis  Pleural effusion       “In-house” Echo   Echo not available

                                                     Obvious LA     Normal or
                                                     enlargement    equivocal LA

                   Fluid analysis,         Congestive heart
                     cytology
                                             failure likely               Additional tests   Consider
                                                                                            respiratory
                                                                                             disease
                                                                 NT-proBNP
                                                                                      Thoracic
                                        Furosemide           high           low      radiography
                                      1–2 mg/kg IV to effect  Cardiomegaly &
                                                              pulmonary infiltrates                   Normal heart

                              If BP <100 mmHg,
                              no murmur
                   Pimobendan
                 1.25 mg q12 h PO


               Figure 27.2  Initial approach to the cat with tachypnea and suspected heart disease. Diagnostic tests are shaded in blue, therapy is
               shaded in pink. A combination of auscultation, rapid and focused “in‐house” ultrasound examination, and other diagnostic tests can
               provide information on probability that the cat’s tachypnea is due to congestive heart failure (CHF) or noncardiac disease. BP, blood
               pressure; Echo, echocardiography; LA, left atrium.

                 Other common causes of a heart murmur in cats    evaluate the potential risk of cardiac complications
               include physiologic (or nonpathologic) murmurs, as well   such as CHF or ATE. Classifying cats as either “low
               as anemia, hyperthyroidism, and hypertension.      risk” or “high risk” facilitates management.


               Is There an Underlying Systemic Cause              Heart Disease Present; High Risk or Low Risk?
               of Myocardial Disease?
                                                                  One of the most useful prognostic indicators for cats
               It is helpful to view feline myocardial disease in terms   with cardiomyopathy is LA size. Cats with HCM and
               of those with and without a specific systemic cause, as   normal LA size can be considered to be at low risk of
               treatment of any underlying cause is essential. It is   CHF and ATE. Cats with LA enlargement fall into a
               vital  to  identify  hypertension,  hyperthyroidism  or   higher risk category. If echocardiography is not available
               anemia, as specific treatment requirements will differ   to  assess  LA  size,  thoracic  radiographs  are  reasonably
               for each. Blood pressure should be measured in all   specific but poorly sensitive to detect LA enlargement.
               cats with suspected heart disease, and T4 concentra-  ARVC is an exception, as LA size is an indicator of risk
               tions measured in older cats. Hematocrit should be   for left heart disease and ARVC predominantly affects
               checked if there is any concern that anemia may be   the right heart. Plasma biomarkers such as NT‐proBNP
               responsible for a murmur. For those cats where no   and troponin‐I can help provide an indication of the
               cause is identified or can be treated, it is important to   severity of heart disease.
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