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224  Section 3  Cardiovascular Disease

            animals receiving ACEIs or ARBs. In many patients,   Proof of improved survival in treated veterinary HT
  VetBooks.ir  improvement may be subtle, but noted by the patient’s   patients is lacking, but because untreated TOD contrib-
                                                              utes to decreased quality of life, untreated HT may lead
            owner as improvements in wakefulness, interest in eating
            and  interaction, and increased activity. Improvement  in
            general quality of life is reported in many patients.  to euthanasia.


              Further Reading


            Acierno MJ, Brown S, Coleman AE, et al. ACVIM       hypertension in client‐owned cats. J Vet Intern Med
              consensus statement: Guidelines for the identification,   2015; 29(3): 786–93.
              evaluation, and management of systemic hypertension   Jepson RE. Feline systemic hypertension: classification and
              in dogs and cats. J Vet Intern Med 2018; 32(6): 1803–22.  pathogenesis. J Feline Med Surg 2011; 13(1): 25–34.
            Coleman AE, Brown SA, Traas AM, et al. Safety and   Sent U, Gössl R, Elliott J, Syme HM, Zimmering T.
              efficacy of orally administered telmisartan for the   Comparison of efficacy of long‐term oral treatment with
              treatment of systemic hypertension in cats: results of a   telmisartan and benazepril in cats with chronic kidney
              double‐blind, placebo‐controlled, randomized clinical   disease. J Vet Intern Med 2015; 29(6): 1479–87.
              trial. J Vet Intern Med 2019; 33(2): 478–88.    Stepien RL. Feline systemic hypertension: diagnosis and
            Huhtinen M, Derré G, Renoldi HJ, et al. Randomized   management. J Feline Med Surg 2011; 13(1): 35–43.
              placebo‐controlled clinical trial of a chewable   Syme H. Hypertension in small animal kidney disease. Vet
              formulation of amlodipine for the treatment of    Clin North Am Small Anim Pract 2011; 41(1): 63–89.
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