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232  Section 3  Cardiovascular Disease

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            Figure 24.1  Gross postmortem specimens of common congenital heart defects. (a) A dog with patent ductus arteriosus; the image is
            taken from a caudal perspective with the descending aorta (Ao) coming toward the viewer. The origin of the ductus (asterisk) within the
            aorta can be seen traversing ventral toward the pulmonary artery, which is seen below as the left (L) and right (R) branches. (b) A dog with
            tricuspid valve dysplasia showing severe right atrial (RA) enlargement, a sheet‐like tricuspid valve with fused, thick leaflets (arrowheads),
            and the ostium of a patent foramen ovale (arrow). (c) A dog with pulmonary valve stenosis showing moderate right ventricular (RV)
            hypertrophy and thickened pulmonary valve leaflets (arrow). (d) A dog with a large ventricular septal defect (arrow), seen in the
            membranous septum at the junction of the left ventricle (LV) and aorta (Ao).

            Ventricular Septal Defects                        to characterize the location of the defect. Exact confir-
            Ventricular septal defects are the most common form of   mation of the size of the defect and secondary cardiac
            CHD in cats, and are also seen in ~9% of dogs with   changes (e.g., aortic insufficiency or left ventricular
            CHD. The pathophysiology of VSD is such that small   enlargement) carry prognostic information for the
            defects (restrictive) may be well tolerated and not result     clients. Additionally, some defects may be in a location
            in overt signs of cardiac dysfunction. Larger defects,   amenable to catheter‐based closure.
            however, result in the shunting of large volumes of blood
            from the left ventricle to the pulmonary circulation. The   Atrial Septal Defects
            result of this increased pulmonary flow is damage to the   As with a VSD, an atrial septal defect is a hole in the
            lung vasculature and volume overload as the blood   intracardiac septum separating the left and right heart.
            returns to the left heart. VSDs can occur in several dif-  ASD is a rare defect in small animals, accounting for
            ferent areas along the interventricular septum and   2–6% of cases. In addition, it is often seen in association
            numerous classification schemes have been developed   with other defects.
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