Page 859 - Small Animal Clinical Nutrition 5th Edition

890 Small Animal Clinical Nutrition

increased hepatic enzyme activity. Antibiotics should also be
VetBooks.ir continued for at least 10 more days.The vitamin-mineral supple-
ment is unnecessary and should be discontinued.

Progress Notes
The azotemia and hyperphosphatemia resolved by the second
day of hospitalization, confirming their prerenal origin. The
combination of amoxicillin and clavulanic acid was continued.
The dog was released from the hospital with instructions for the
owner to give 2-MPG at a dosage of 15 mg/kg body weight, per
os, twice daily.The food was changed to moist Prescription Diet
u/d Canine and the vitamin-mineral supplement was discontin-
ued. Radiographs taken 40 days after initial hospitalization
showed no evidence of uroliths (Figure 3). Urinalysis results
included un-concentrated alkaline urine with amorphous crys-
Figure 3. Double-contrast cystogram of the dog described in
tals. The serum urea nitrogen concentration was 4 mg/dl, which
Figures 1 and 2 taken 40 days after initiation of therapy with 2-MPG
and Prescription Diet u/d Canine. There are no uroliths in the blad- confirmed that the low-protein food was being fed at home. 2-
der lumen. Contrast urethrography confirmed that there were no MPG was discontinued and Prescription Diet u/d Canine was
uroliths in the urethral lumen. continued. Examination 75 and 232 days after initial hospitaliza-
tion revealed that the urine continued to be un-concentrated and
alkaline with no evidence of crystalluria. The urea nitrogen concentration remained low (5 to 6 mg/dl), which indicated that the
owner was compliant with the feeding plan.

Endnotes
a. Pfizer Animal Health, Exton, PA, USA.
b. Thiola. Mission Pharmacal, San Antonio, TX, USA.
c. Hill’s Pet Nutrition, Inc., Topeka, KS, USA.

Bibliography
Osborne CA, Lulich JP, Bartges JW, et al. Canine and feline urolithiasis: Relationship of etiopathogenesis to treatment and pre-
vention. In: Osborne CA, Finco DR, eds. Canine and Feline Nephrology and Urology. Baltimore, MD: Williams & Wilkins, 1995;
798-888.