Page 1041 - Saunders Comprehensive Review For NCLEX-RN
P. 1041

1. The test produces a positive reaction 2 to 10 weeks
                                                after the initial infection.
                                             2. The test determines whether a child has been infected
                                                and has developed a sensitivity to the protein of the
                                                tubercle bacillus; a positive reaction does not confirm
                                                the presence of active disease (exposure versus
                                                presence).
                                             3. After a child reacts positively, the child will always
                                                react positively; a positive reaction in a previously
                                                negative child indicates that the child has been
                                                infected since the last test.

                                                      4. Tuberculosis testing should not be done at the

                                                same time as measles immunization (viral
                                                interference from the measles vaccine may cause a
                                                false-negative result).
                                D. Sputum culture
                                             1. A definitive diagnosis is made by showing the
                                                presence of mycobacteria in a culture.
                                             2. Chest x-rays are supplemental to sputum cultures and
                                                are not definitive alone.

                                                      3. Because an infant or young child often

                                                swallows sputum rather than expectorates it, gastric
                                                washings (aspiration of lavaged contents from the
                                                fasting stomach) may be done to obtain a specimen;
                                                the specimen is obtained in the early morning before
                                                breakfast.
                                E. Interventions
                                             1. Medications
                                                             a. A 9-month course of isoniazid may be
                                                                prescribed to prevent a latent infection
                                                                from progressing to clinically active
                                                                tuberculosis and to prevent initial
                                                                infection in children in high-risk
                                                                situations; a 12-month course may be
                                                                prescribed for a child infected with
                                                                human immunodeficiency virus (HIV).
                                                             b. Recommendation for a child with
                                                                clinically active tuberculosis may
                                                                include combination administration of
                                                                isoniazid, rifampin, and pyrazinamide
                                                                daily for 2 months, and then isoniazid
                                                                and rifampin twice weekly for 4
                                                                months.
                                                             c. Inform the parents and child that bodily
                                                                fluids, including urine, may turn an




                                                         1041
   1036   1037   1038   1039   1040   1041   1042   1043   1044   1045   1046