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2. Gastrointestinal irritation, nausea
3. Dry mouth
4. Constipation
5. Respiratory depression
C. Interventions
1. Encourage the client to take adequate fluids with the
medication.
2. Encourage the client to sleep with the head of the bed
elevated.
3. Note that medication dependency can occur.
4. Avoid administration to the client with a head
injury or a postoperative cranial surgery client.
5. Avoid administration to the client using
opioids, sedative-hypnotics, barbiturates, or select
antidepressants, because CNS depression can occur.
D. Client education
1. If the cough lasts longer than 1 week and a fever or
rash occurs, to notify the PHCP
2. To avoid hazardous activities
3. To avoid the use of alcohol
XII. Opioid Antagonists (Box 51-6)
A. Description
1. Reverses respiratory depression in opioid overdose
2. Avoid its use for nonopioid respiratory depression.
3. Reoccurrence of respiratory depression can occur if
duration of opiate exceeds duration of opioid
antagonist.
4. This medication may be prescribed for clients at risk
for opioid overdose.
5. https://www.nsc.org/home-safety/safety-topics/
opioids/prescription-nation?
gclid=EAIaIQobChMIiJXd446a2wIViYizCh0-
_ADOEAAYASAAEgKfc_D_BwE
B. Side and adverse effects
1. Nausea, vomiting
2. Tremors
3. Sweating
4. Increased blood pressure
5. Tachycardia
C. Interventions
1. Assess vital signs, especially respirations.
2. For intravenous administration, the dose is titrated
every 2 to 5 minutes as prescribed.
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