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administration. Alcohol should be avoided with the use of medications.
                  Level of Cognitive Ability: Applying
                  Client Needs: Physiological Integrity
                  Integrated Process: Teaching and Learning
                  Content Area: Pharmacology: Musculoskeletal Medications: Muscle Relaxants
                  Health Problem: Adult Health: Musculoskeletal: Tissue or ligament injury
                  Priority Concepts: Client Education; Safety
                  Reference: Hodgson, Kizior (2018), pp. 113-114.


                   759. Answer: 3


                  Rationale: Dose-related liver damage is the most serious adverse effect of
               dantrolene. To reduce the risk of liver damage, liver function tests should be
               performed before treatment and throughout the treatment interval. Dantrolene is
               administered at the lowest effective dosage for the shortest time necessary.
                  Test-Taking Strategy: Eliminate options 2 and 4 because these tests assess kidney
               function and are comparable or alike. From the remaining options, you must recall
               that this medication affects liver function.
                  Level of Cognitive Ability: Analyzing
                  Client Needs: Physiological Integrity
                  Integrated Process: Nursing Process—Analysis
                  Content Area: Pharmacology: Musculoskeletal Medications: Muscle Relaxants
                  Health Problem: Adult Health: Musculoskeletal: Tissue or ligament injury
                  Priority Concepts: Cellular Regulation; Tissue Integrity
                  Reference: Lilley et al. (2017), p. 198.


                   760. Answer: 1


                  Rationale: Because cyclobenzaprine has anticholinergic effects, it should be used
               with caution in clients with a history of urinary retention, glaucoma, and increased
               intraocular pressure. Cyclobenzaprine should be used only for a short time (2 to 3
               weeks). The conditions in options 2, 3, and 4 are not a concern with this medication.
                  Test-Taking Strategy: Focus on the subject, a contraindication to cyclobenzaprine.
               Recalling that this medication has anticholinergic effects will direct you to the correct
               option.
                  Level of Cognitive Ability: Analyzing
                  Client Needs: Physiological Integrity
                  Integrated Process: Nursing Process—Analysis
                  Content Area: Pharmacology: Musculoskeletal Medications: Muscle Relaxants
                  Health Problem: Adult Health: Musculoskeletal: Tissue or ligament injury
                  Priority Concepts: Collaboration; Safety
                  Reference: Skidmore-Roth (2017), pp. 300-301.


                   761. Answer: 1, 2, 3, 4


                  Rationale: Because emotional stress frequently exacerbates the symptoms of
               rheumatoid arthritis, the absence of symptoms is a positive finding. DMARDs are



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