Page 2163 - Saunders Comprehensive Review For NCLEX-RN
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Rationale: Colchicine is used with caution in older clients, debilitated clients, and
               clients with cardiac, kidney, or gastrointestinal disease. The disorders in options 1, 3,
               and 4 are not concerns with administration of this medication.
                  Test-Taking Strategy: Focus on the subject, the cautions associated with
               colchicine. Note that options 1, 3, and 4 are comparable or alike and are endocrine-
               related disorders. The correct option is different from the others.
                  Level of Cognitive Ability: Analyzing
                  Client Needs: Physiological Integrity
                  Integrated Process: Nursing Process—Analysis
                  Content Area: Pharmacology: Musculoskeletal Medications: Antigout
                  Health Problem: Adult Health: Musculoskeletal: Gout
                  Priority Concepts: Clinical Judgment; Safety
                  Reference: Lilley et al. (2017), pp. 701, 703.


                   757. Answer: 4


                  Rationale: Precautions need to be taken with the administration of alendronate to
               prevent gastrointestinal adverse effects (especially esophageal irritation) and to
               increase absorption of the medication. The medication needs to be taken with a full
               glass of water after rising in the morning. The client should not eat or drink anything
               for 30 minutes following administration and should not lie down after taking the
               medication.
                  Test-Taking Strategy: Focus on the subject, the administration of alendronate.
               Recalling that this medication can cause esophageal irritation will direct you to the
               correct option.
                  Level of Cognitive Ability: Applying
                  Client Needs: Physiological Integrity
                  Integrated Process: Teaching and Learning
                  Content Area: Pharmacology: Musculoskeletal Medications: Osteoporosis
               Medications
                  Health Problem: Adult Health: Musculoskeletal: Osteoporosis
                  Priority Concepts: Client Education; Tissue Integrity
                  Reference: Lilley et al. (2017), p. 542.


                   758. Answer: 2


                  Rationale: Baclofen is a skeletal muscle relaxant. The client should be cautioned
               against the use of alcohol and other central nervous system depressants, because
               baclofen potentiates the depressant activity of these agents. Constipation, rather than
               diarrhea, is a side effect. Restriction of fluids is not necessary, but the client should
               be warned that urinary retention can occur. Fatigue is related to a central nervous
               system effect that is most intense during the early phase of therapy and diminishes
               with continued medication use. The client does not need to notify the PHCP about
               fatigue.
                  Test-Taking Strategy: Focus on the subject, teaching points for baclofen. Recalling
               that baclofen is a skeletal muscle relaxant will direct you easily to the correct option.
               If you were unsure of the correct option, use general principles related to medication



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