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▪ Chlorzoxazone

                  ▪ Cyclobenzaprine
                  ▪ Dantrolene
                  ▪ Diazepam
                  ▪ Metaxalone
                  ▪ Methocarbamol
                  ▪ Orphenadrine
                  ▪ Tizanidine



               Box 61-2

               Antiarthritic Medications



                  ▪ Anakinra
                  ▪ Adalimumab
                  ▪ Azathioprine
                  ▪ Cyclosporine
                  ▪ Etanercept
                  ▪ Hydroxychloroquine
                  ▪ Infliximab
                  ▪ Leflunomide

                  ▪ Methotrexate
                  ▪ Penicillamine
                  ▪ Rituximab
                  ▪ Sulfasalazine























                           FIG. 61-1  Progressive joint degeneration in rheumatoid arthritis. A, Healthy joint. B,
                         Inflammation of synovial membrane. C, Onset of pannus formation and cartilage erosion.
                             D, Pannus formation progresses and cartilage deteriorates further. E, Complete
                                  destruction of joint cavity, together with fusion of articulating bones.







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