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P. 2158

bisphosphonates must be administered in the
                                                                morning before eating or drinking with a full glass of
                                                                water; the client must then remain sitting or standing
                                                                and postpone ingesting anything for at least 30
                                                                minutes (60 minutes with ibandronate).
                                             3. Raloxifene
                                                             a. Antiresorptive medication
                                                                (nonbisphosphonate)

                                                                    b. Contraindicated in clients who

                                                                have a history of venous thrombotic
                                                                events
                                                             c. Needs to be discontinued 72 hours prior
                                                                to prolonged immobilization periods
                                                                (such as with periods of extended bed
                                                                rest)
                                                             d. Instruct the client to avoid extended
                                                                periods of restricted activity (such as
                                                                when traveling).
                                             4. Denosumab: A monoclonal antibody that treats
                                                osteoporosis and hypercalcemia; can also treat bone
                                                cancer and bone problems in those who have cancer.
                                             5. Teriparatide
                                                             a. Teriparatide stimulates new bone
                                                                formation, thus increasing bone mass.
                                                             b. Teriparatide is a portion of the human
                                                                parathyroid hormone and works by
                                                                increasing the action of osteoblasts.
                                                             c. Is usually reserved for clients at high
                                                                risk for fractures

                                                             d.        Has been associated with the

                                                                development of bone cancer




                                                                       NSAIDs such as ibuprofen, indomethacin,

                                                                and naproxen are commonly used to treat
                                                                musculoskeletal pain. Acetaminophen may also be
                                                                used to treat this type of pain as well and are often
                                                                considered first-line treatments.



               Box 61-1

               Skeletal Muscle Relaxants


                  ▪ Baclofen
                  ▪ Carisoprodol



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