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supplements).
                                             3. Treatment is aimed at reducing the occurrence of
                                                fractures by maintaining or increasing bone strength.
                                             4. Medications that decrease bone resorption
                                                (antiresorptive) and medications that promote bone
                                                formation are used (Box 61-3).
                                             5. Antiresorptive medications include raloxifene,
                                                calcitonin, and bisphosphonates.
                                             6. Teriparatide promotes bone growth.

                                        B. Interventions

                                             1. Calcitonin-salmon
                                                             a. Calcitonin is secreted by the thyroid
                                                                gland and inhibits osteoclastic bone
                                                                resorption.
                                                             b. Instruct the client on how to administer
                                                                the intranasal or subcutaneous form,
                                                                depending on the route prescribed.

                                                                    c. Intranasal route: Examine the

                                                                nares for irritation; alternate nostrils
                                                                for doses.

                                                                    d. When calcitonin is taken, it is

                                                                important to monitor for
                                                                hypocalcemia.
                                             2. Bisphosphonates
                                                             a. Bisphosphonates inhibit osteoclast-
                                                                mediated bone resorption, thereby
                                                                increasing total bone mass.
                                                             b. Bisphosphonates include alendronate,
                                                                risedronate, ibandronate, pamidronate,
                                                                and zoledronic acid.

                                                                    c. Contraindicated for clients with

                                                                esophageal disorders that can impede
                                                                swallowing and for clients who cannot
                                                                sit or stand for at least 30 minutes (60
                                                                minutes with ibandronate)
                                                             d. Adverse effects include esophagitis,
                                                                muscle pain, and ocular problems; the
                                                                client is instructed to contact the PHCP
                                                                if adverse effects occur.




                                                                       Because of the risk of esophagitis,




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