Page 68 - Heart Transplant Protocol

Heart Function Service: Heart Transplant Protocols

 IgG (for deficiency) post-tx
 Renal function tests
 Cardiac monitoring
 Liver function tests
 Neurological changes for PML

Toxicology:
Treatment is symptomatic and supportive.

Immune hypersensitivity reaction: Discontinue infusion. Oxygen therapy, bronchodilators,
diphenhydramine, corticosteroids vasopressors and epinephrine may be required depending on the
severity of the infusion reaction.

Hemodialysis: Dialysis may be indicated in patients that develop acute renal failure related to tumor lysis
syndrome.

Myelosuppression: Administer colony stimulating factor in patients with severe granulocytopenia.
Filgrastim - 5 mcg/kg/day IV or SQ. Sargramostim - 250 mcg/meter(2)/day IV over 4 hours; transfusion
for severe thrombocytopenia or bleeding.

Updated November 9, 2017 68