Page 73 - Heart Transplant Protocol

Heart Function Service: Heart Transplant Protocols

3. Stop infusions and notify prescriber if patient develops:

 Chest tightness
 Diaphoresis
 Hypertension
 Hypotension
 Rash
 Urticaria

4. Slow or stop infusion notify prescriber if patient develops reduced urine output

5. Notify prescriber if patient develops during infusion or if reaction occurs 10 to 12 hours after
completion the infusion:

 Rapid-onset severe headache
 Stiff neck or
 Photophobia

Attachment C

IVIG Monitoring Protocols

Possible adverse Monitoring Management of Comments
reactions parameters adverse reaction
Infusion related Monitor vital signs 1. Slow infusion until Reactions with
reactions: Mild to every 15 minutes until symptoms resolve OR subsequent infusions
moderate hypotension, the maximum infusion stop infusion may be
headache, fever/chills, rate is reached. Check 2. Contact provider prevented/reduced by
nausea/vomiting, vital signs hourly after 3. Call the ADR hotline pretreatment with
flushing, pruritus, reaching the maximum to report a reaction acetaminophen,
urticarial, infusion rate and at the diphenhydramine, or
lightheadedness, completion of the corticosteroids.
myalgia, fatigue, and infusion.
mild hypertension
Signs of anaphylaxis: Monitor vital signs 1. Stop infusion AND Low IgA content
chest tightness, every 15 minutes until contact provider products may be
diaphoresis, the maximum infusion 2. Call the ADR hotline administered with
tachycardia, rate is reached. Check to report the reaction caution to patients with
hypertension, vital signs hourly after antibodies to IgA or
hypotension, rash, reaching the maximum selective IgA
urticaria infusion rate and at the deficiencies
completion of the
infusion (Gamunex contains low
quantity of IgA)

Updated November 9, 2017 73