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CHAPTER 30 Antidepressant Agents 551
PREP AR A TIONS Barrera AZ, Torres LD, Munoz RF: Prevention of depression: The state of the sci-
ence at the beginning of the 21st century. Int Rev Psychiatry 2007;19:655.
A V AIL ABLE Bellingham GA, Peng PW: Duloxetine: A review of its pharmacology and use in
chronic pain management. Reg Anesth Pain Med 2010;35:294.
GENERIC NAME AVAILABLE AS Belmaker R, Agam G: Major depressive disorder. N Engl J Med 2008;358:55.
SELECTIVE SEROTONIN REUPTAKE INHIBITORS Bockting CL et al: Continuation and maintenance use of antidepressants in recur-
rent depression. Psychother Psychosom 2008;77:17.
Citalopram Generic, Celexa Bonisch H, Bruss M: The norepinephrine transporter in physiology and disease.
Escitalopram Generic, Lexapro Handb Exp Pharmacol 2006;175:485.
Fluoxetine Generic, Prozac, Prozac Weekly Castren E, Voikar V, Rantamaki T: Role of neurotrophic factors in depression.
Curr Opin Pharmacol 2007;7:18.
Fluvoxamine * Generic Chaki S et al: mGlu2/3 and mGlu5 receptors: Potential targets for novel antide-
Paroxetine Generic, Paxil pressants. Neuropharmacology 2013;66:40.
Sertraline Generic, Zoloft Chappell AS et al: A double-blind, randomized, placebo-controlled study of the
SEROTONIN NOREPINEPHRINE REUPTAKE INHIBITORS efficacy and safety of duloxetine for the treatment of chronic pain due to
Desvenlafaxine Pristiq osteoarthritis of the knee. Pain Pract 2011;11:33.
Duloxetine Generic, Cymbalta Chen G et al: Pharmacokinetic drug interactions involving vortioxetine
(Lu AA21004), a multimodal antidepressant. Clin Drug Investig 2013;33:727.
Levomilnacipran Fetzima Cipriani A et al: Fluoxetine versus other types of pharmacotherapy for depression.
Milnacipran † Savella Cochrane Database Syst Rev 2005;4:CD004185.
Venlafaxine Generic, Effexor Cipriani A et al: Metareview on short-term effectiveness and safety of antidepres-
5-HT RECEPTOR MODULATORS sants for depression: An evidence-based approach to inform clinical practice.
Can J Psychiatry 2007;52:553.
Nefazodone Generic Citrome L: Vortioxetine for major depressive disorder: A systematic review of the
Trazodone Generic, Desyrel efficacy and safety profile for this newly approved antidepressant—What is
Vortioxetine Trintellix the number needed to treat, number needed to harm and likelihood to be
TRICYCLICS helped or harmed? Int J Clin Pract 2014;68:60.
Amitriptyline Generic, Elavil de Beaurepaire R: Questions raised by the cytokine hypothesis of depression. Brain
Behav Immun 2002;16:610.
Amoxapine Generic Dhillon S, Scott LJ, Plosker GL: Escitalopram: A review of its use in the manage-
Clomipramine * Generic, Anafranil ment of anxiety disorders. CNS Drugs 2006;20:763.
Desipramine Generic, Norpramin Dhillon S, Yang LP, Curran MP: Bupropion: A review of its use in the management
of major depressive disorder. Drugs 2008;68:653.
Doxepin Generic, Sinequan Duman RS, Monteggia LM: A neurotrophic model for stress-related mood disor-
Imipramine Generic, Tofranil ders. Biol Psychiatry 2006;59:1116.
Nortriptyline Generic, Pamelor Dvir Y, Smallwood P: Serotonin syndrome: A complex but easily avoidable condi-
Protriptyline Generic, Vivactil tion. Gen Hosp Psychiatry 2008;30:284.
Trimipramine Surmontil Fontenelle LF et al: An update on the pharmacological treatment of obsessive-
TETRACYCLIC AND UNICYCLIC AGENTS compulsive disorder. Expert Opin Pharmacother 2007;8:563.
Amoxapine Generic Geisser ME et al: A pooled analysis of two randomized, double-blind, placebo-
controlled trials of milnacipran monotherapy in the treatment of fibromyal-
Bupropion Generic, Wellbutrin gia. Pain Pract 2011;11:120.
Maprotiline Generic Gether U et al: Neurotransmitter transporters: Molecular function of important
Mirtazapine Generic, Remeron drug targets. Trends Pharmacol Sci 2006;27:375.
Vilazodone Viibryd Gillespie CF, Nemeroff CB: Hypercortisolemia and depression. Psychosom Med
2005;67(Suppl 1):S26.
MONOAMINE OXIDASE INHIBITORS Gillman PK: A review of serotonin toxicity data: Implications for the mechanisms
Isocarboxazid Marplan of antidepressant drug action. Biol Psychiatry 2006;59:1046.
Phenelzine Generic, Nardil Gillman PK: Tricyclic antidepressant pharmacology and therapeutic drug interac-
Selegiline Generic, Eldepryl tions updated. Br J Pharmacol 2007;151:737.
Tranylcypromine Generic, Parnate Giner L et al: Selective serotonin reuptake inhibitors and the risk for suicidality in
adolescents: An update. Int J Adolesc Med Health 2005;17:211.
* Labeled only for obsessive-compulsive disorder. Guay DR: Vilazodone hydrochloride, a combined SSRI and 5-HT1A receptor
† agonist for major depressive disorder. Consult Pharm 2012;27:857.
Labeled only for fibromyalgia.
Gutman DA, Owens MJ: Serotonin and norepinephrine transporter binding pro-
file of SSRIs. Essent Psychopharmacol 2006;7:35.
Harrison J, et al: The effects of vortioxetine on cognitive function in patients with
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