Page 755 - Atlas of Histology with Functional Correlations

The main action of ADH is to increase water permeability in the distal

convoluted tubules and collecting ducts of the kidney. As a result, more
water is reabsorbed from the filtrate into the interstitium and retained in the
body, creating more concentrated urine. In addition, an increase in blood
tonicity or a decrease in blood volume stimulates the osmoreceptor cells in
the hypothalamus to activate the release of ADH from the neurons in the

neurohypophysis. Increased water retention/absorption through ADH action
on the kidney tubules increases fluid volume and restores the osmotic
balance of body fluids.

Summary

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