Page 44 - Org 3 theoritical book 2024-25
P. 44

Clinical Pharmacy PharmD - 2024/2025                  Level 2                Pharmaceutical Organic Chemistry-3 (PC 305)
                 3.  Oxidation


            Thiophene ring is decomposed on oxidation.


            Substituted  thiophene  could  be  oxidized  with  the  specific  oxidizing  agent

            peroxycarboxylic  acid  (eg.  perbenzoic  acid)  to  give  the  non-aromatic  isolable

            sulphone.


                                                      PhCOOOH
                              H C             CH 3                     H C             CH 3
                                                                        3
                                3
                                        S                                       S
                                                                             O     O
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