Page 81 - Org 3 theoritical book 2024-25
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Clinical Pharmacy PharmD - 2024/2025                  Level 2                Pharmaceutical Organic Chemistry-3 (PC 305)
            Other Biologically Important Sugars


               Monosaccharides  in  which  an  OH  group  has  been  replaced  by  H  are  known  as

               deoxy  sugars.  The  most  important  deoxy  sugar,  because  it  occurs  in  DNA,  is

               deoxyribose.  Other  deoxy  sugars  that  occur  widely  in  polysaccharides  are  L-


               rhamnose and L-fucose.















            Sugars That Contain Nitrogen


               a) Glycosylamines


               A sugar in which an amino group replaces the anomeric OH.

               Examples are β-D-glucopyranosylamine and adenosine.




















               b) Amino Sugars

               A sugar in which an amino group replaces a non-anomeric OH group.

               D-Glucosamine is an example of an amino sugar.

               In many instances the amino group is acetylated as in N-acetyl-D-glucosamine.

                N-Acetylmuramic acid is an important component of bacterial cell walls.
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