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A Special Thank Breast Cancer... Breast Cancer... Breast Cancer...

You to the Cover Story: 2017: What Is New in Cancer Care?

September 2017
Continued from page 1 problem. Palbociclib is a drug that block these checkpoints and have trans-
Host of the South approaches. Midostaurin, a drug that blocks CDK4 therefore diminishing the formed the outcomes of many cancers.
targets mutation FLT3 became the first hormone resistance mechanism of breast Over the past year, the FDA approved
Florida Healthcare drug approved for acute myeloid cancer. Clinical trials demonstrated bet- five new uses for immune checkpoint
leukemia treatment after 20 years.
ter tumor control; therefore, it is
inhibitors: lung cancer, head and neck
Inotuzumab ozogamicin is a novel treat- approved by the FDA in combination cancer, bladder cancer, kidney cancer
Networking Group ment which is an antibody–drug conju- with hormone therapy. and Hodgkin lymphoma. Atezolizumab,
gate that improves delivery of the drug In other cancer types, new develop- an immunotherapy, is the first new treat-
into the cancer cell. This new drug may ments also occurred. In kidney cancer, ment for bladder cancer in 30 years.
improve outcomes for older people with cabozantinib is a drug that targets vascu- Recently, the FDA approved first CAR-T
recurrent acute lymphoblastic leukemia. lar endothelial growth factor receptor cell therapy (tisagenlecleucel) for acute
Progress is also noted in non-small and has been shown that it was more lymphoblastic leukemia. These cells are
cell lung cancers. In patients with ALK effective compared to standard of care genetically modified to include a new
mutations alectinib treatment produced patients with recurrent disease. In gene that targets the cancer cell. This
MEMORIAL encouraging results in patients resistant patients with glioma, which is a brain development may be the beginning of a
HOSPITAL to first line therapy including those with tumor, adding chemotherapy to radia- new era.
brain metastases. tion extended glioma survival. This Relentless work to conquer cancer is
MIRAMAR Multiple myeloma is a cancer of plas- study led to a change in the standard of ongoing. Each year, our knowledge of
ma cells, which are found in the blood care for high-risk gliomas. In colon can- cancer grows and many new treatments
that produce antibodies to fight infec- cer, studies have showed that patients are being developed in an effort to
For information about tions. CD38 is a molecule that is with advanced colorectal cancer with improve the outlook for patients with
expressed on plasma cells. left-side tumors of the colon survived cancer.
our next meeting of
Daratumumab is a drug that targets longer compared to right-side tumors.
SFHNG, CD38 and a study has shown that incor- Now the clinicians have taken into
poration of daratumumab to standard account the location of the primary Dr. Mehmet F. Hepgur is a
please email
regimen reduced lower risk of cancer tumor. Hematologist/Oncologist on staff at the
charles@ progression by 70%. Immune checkpoints such as PD-1 or Comprehensive Cancer Center at Broward
Hormone receptor–positive breast CTLA-4 are usually exploited by the Health Medical Center.
southfloridahospitalnews.com
cancer is the most common type of tumor to suppress that immune Dr. Hepgur is also a Clinical Assistant
breast cancer. Hormone therapy is the response against tumor. In just a few Professor for the Dept. of Internal Medicine
standard of care but resistance is a huge short years, immunotherapies mainly at Nova Southeastern University.

THE REGION’S MONTHLY NEWSPAPER FOR HEALTHCARE PROFESSIONALS & PHYSICIANS
High Risk Screening Program
at Jupiter Medical Center

Can Give Your Patients an Edge

in the Fight Against Breast Cancer
Telemedicine While many women may know that • A personal history or prior radiation

and Telemetry breast cancer is the second-leading cause therapy to the chest
of cancer death in women, they may not • Known or suspected to carry the
know their own personal risk of devel- BRCA 1 and/or BRCA2 gene mutations
oping the disease. Staffed by highly The High Risk Breast Screening
trained physicians, genetic counselor Program at Jupiter Medical Center helps
and nurse navigator, the High Risk each patient understand the impact of
Breast Cancer Screening Program at their family’s cancer history and provides
Jupiter Medical Center provides a wide testing for patients who may have genet-
array of services to help your patients ic risk factors. In addition, Jupiter
• On site and remote access to medical specialists learn more about their risk factors and Medical Center’s Margaret W. Niedland
develop a plan for breast care surveil- Breast Center is equipped with state-of-
24-hour/day for high risk patients lance. the-art screening technologies to detect
We know that breast cancer, like many breast cancer at the earliest possible
• Real time feedback during physical therapy to monitor other forms of cancer, can be treated stage. From 3-D mammography with the
treatment regimens and responses most effectively when it is identified at lowest radiation dose, to ultrasound
an early stage, which is why we recom- breast imaging, bone density testing and
• Faster interventions to reduce ER transfers, hospital mend that women be proactive about a specialized MRI with Caring Suite to
monitoring their breast health. Women
deliver soothing sights and sounds,
admissions and readmissions who are positive for any of the following Jupiter Medical Center will help you
risk factors should be especially proac- monitor and manage your patient’s
tive: breast health. As an added benefit, the
• Two or more relatives from the same Margaret W. Niedland Breast Center also
side of the family diagnosed with breast offers a beautiful outdoor meditation
Award Winning Rehabilitation & Skilled Nursing Centers
cancer at any age garden to relax the body and mind.
• One relative diagnosed with breast Knowledge is power when it comes to
cancer before age 50, or a relative with preventing breast cancer. Jupiter Medical
Available now at:
an ovarian cancer diagnosis at any age Center’s High Risk Breast Screening
• A male relative with breast cancer Program can help arm your patients with
Arch Plaza | Aventura Plaza | Jackson Plaza | Ponce Plaza • Any family history of breast or ovar- more knowledge to keep them healthy.
Sinai Plaza | South Pointe Plaza | University Plaza ian cancer and of Ashkenazi Jewish
decent
• A personal history of breast cancer, For more information, call Allison Kern,
Learn more at plazahealth.org/telemedicine not-for-profit 501(C)(3) atypia or lobular carcinoma insitu practice manager, at (561) 263-7597.

20 October 2017 southfloridahospitalnews.com South Florida Hospital News