Page 7 - EUREKA! Summer 2018
P. 7

Image courtesy Dr. James Heilman








                                                                Fine-tuning cancer care




                                                                     bout half of all cancer patients — and 20 percent
                                                                     of all Canadians — will get radiation therapy as part
                                                                Aof their medical care. These statistics, and the fact
                                                                that radiation damages healthy cells while destroying
                                                                cancer cells, speaks to the need to develop more precise
                                                                approaches to cancer treatment. Brachytherapy, which
                                                                entails implanting small radioactive sources roughly the
 Go green                                                       targeted, has been evolving as a technique for more than a
                                                                size of a grain of rice (pictured above) near the area being

                                                                century, with medical physicists such as Carleton professor
                                                                Rowan Thomson working to help refine the treatment.
                                                                  The standard protocol for brachytherapy begins with
 Gauging the health benefits                                    deciding where to position the radioactive sources, either
                                                                high-dose temporary implants or low-dose and permanent.
                                                                Afterward, a CT scan is done to determine the actual
 of getting active in urban nature                              source locations; this information is used to calculate
                                                          Photo: Richard Hinchcliff  of the treatment. Thomson and her collaborators at the
                                                                doses, and further analyses evaluates the effectiveness

                                                                Ottawa Medical Physics Institute are part of an effort to
                                                                come up with more accurate dose calculation algorithms —
                                                                using Monte Carlo or probability simulations — and she is
                                                                also a member of a task force that’s developing guidelines
                                                                for bringing these ideas from the research stage to clinical
                                                                practice.
 here is evidence of several health benefits associated   behaviours that increase the risk of chronic disease.”  used Ottawa area bike paths.  One of Thomson’s current projects revolves around “egs
 with neighbourhood greenness, but reasons for this   The preceding text is taken from a paper published last   “Greenness in urban areas has been linked to a number   brachy,” an open-source code for rapid brachytherapy
 Tare unclear. Studies have found that those who live   year in the journal Environmental Research by Carleton   of healthy behaviours, including reduced obesity and   dose calculations (“egs” is short for electron gamma
 in greener neighbourhoods are more physically active, and   Health Sciences professor Paul Villeneuve, an epidemiologist   increased participation in physical activity, and facilitates   shower) developed at Carleton. It’s currently being tested
 have lower rates of obesity. Relatively few studies have   and biostatistician cross-appointed to the School of   social interaction that come with its own health benefits,”   on 40 patients in Kelowna, B.C., where brachytherapy is
 attempted to characterize associations between greenness   Mathematics and Statistics. Villeneuve and his students have   Villeneuve wrote in an email to the Ottawa Citizen.   common because many cancer patients in the region live
 and both obesity and physical activity concurrently, or   also done research showing that the four square kilometres   “Greenness in urban areas has also been linked to a   in remote locations and cannot easily come to the city
 among women who are at higher risk of developing cancer   of green space in Ottawa’s Central Experiment Farm —   number of important health outcomes including improved   for treatment. “Medical doctors prescribe radiation as
 and for whom physical activity may be important for   where the accompanying photo was taken — improves air   sleep quality, reduced stress and lower mortality. These   a treatment,” says Thomson, Canada Research Chair in
 primary prevention…. Our findings indicate that, amongst   quality, reduces pollution and lowers temperatures in the   effects have been observed in both affluent and low-  Radiotherapy Physics, “and medical physicists study the
 U.S. adult women at higher risks of breast cancer, residential   surrounding area. This summer, they will begin mapping air   income neighbourhoods.”  interaction of radiation and matter so we can improve the
 proximity to greenness may help mitigate against sedentary   pollution, noise and temperature measures along commonly   care patients receive.”



 6  science.carleton.ca                                                                           science.carleton.ca  7
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