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INTER VIE WS                                                                               INTER VIE WS





 Emeritus Professor   After completing a PhD at the University of Melbourne what
 led you to undertake postgraduate research in the UK? Can you
 Keryn Williams AC   tell us about your journey and experience, and do you have
 (1968) is interviewed   any advice for those also considering postgraduate research
 overseas?
 by JCH science
 student, Anna   During my PhD candidature, the laboratory in which I was
 embedded – in the School of Microbiology – ran a shared
 Tsuchida-Gorbal   seminar program with a laboratory across Royal Parade, in the
 (2024)  Royal Melbourne Hospital’s Department of Surgery. The head
 of the latter laboratory was a vascular surgeon, Peter Morris,
 whose major focus was renal transplantation. During the last
 year or so of my candidature, Morris was recruited to the Chair
 of the Nuffield Department of Surgery at the University of
 Oxford. He offered me a junior post-doctoral position there
 and, the day after I handed up my thesis, I hopped on a plane
 Why did you choose to go to JCH and study science at
 Melbourne University? Was scientific research always an end   for England. I was expecting to stay a year – I stayed for almost
 goal or was the journey a little less linear?    seven.
 I relished my time in England. I loved the research, but I also
 One night in the summer of 1957, my father carried me, clad in
 my pyjamas, out into the back garden to watch Sputnik pass   enjoyed the experiences of different ways of doing almost
 across the sky overhead. It was amazing: like a fast-moving   everything. Can’t say I much enjoyed the freezing fogs of
 star. Dad explained that scientists had designed this first-ever   November but one survives. For those considering an overseas   Some of the Australian Corneal Graft Registry team
 artificial satellite, and I think perhaps my path was set then. I   post-doc, select a place that you and any accompanying family
 chose the maths and science streams at school, even though I   members will enjoy, and that is relatively safe.
 felt I was never really very good at either. I wanted to become      In 1985 we established the Australian Corneal Graft Registry,   Could you share some insights with us about your roles within
 some sort of scientist – but which sort?  What led you to specialise in corneal transplantation? Has this   so I can report that about 2,000 Australians receive a corneal   the university sector and academia? Many students are
 always been a passion of yours, or is it an area of interest you   transplant every year and that outcomes have slowly but   considering the private and public sectors. Do you have any
 Without having the foggiest idea about what the future might   developed along your journey?   steadily improved – the result, I suggest, of 50 years’ worth of   advice for those unsure which to choose?

 bring, I chose first-year biology, chemistry, physics and maths      research. My colleagues, many of whom are clinician scientists,   No need to obsess over the choice, because you can move
 subjects at the University of Melbourne. For that first year, I   In Oxford, I was immersed in research into the immunobiology   research other eye conditions and diseases – for example,   backwards and forwards between the public and private
 lived at home and travelled into university each day by tram.   of clinical organ transplantation, but in late 1980 family dynamics     glaucoma and uveitis – and I think that overall, understanding   sectors and many people do. Maybe once it was difficult, but
 The travelling was a time-wasting chore, and I was so envious of   necessitated a return to Australia. By chance, a clinician who   is growing and leading to better outcomes. Blindness may not   really, no longer: it’s a two-way street. I’ve spent my working life
 the students who lived on campus. I was fortunate enough to   was setting up a new Department of Ophthalmology at Flinders   be a life-threatening condition but for the individual affected, it   within the academic sector but have enjoyed several productive
 score well enough in the end-of-year exams to win a residential   University was looking for a scientist to join his team. The first   has many consequences.   collaborations with those in industry. Grab such opportunities
 part-scholarship at JCH, where I thrived: I loved everything   day I turned up in Adelaide, eager but clueless, Professor Doug      when they arise because you never know where they will lead.
 about College life.  Coster described the human cornea to me and gave me an   What is it like to pursue scientific research? Could you share
 open-ended but intriguing brief: to insert some science into the   what a typical day in the life of a researcher or professor looks
 Biochemistry (my initial goal) turned out to be less interesting   art of corneal transplantation. I seized the opportunity and have   like?   What are your passions outside of research? What do you do to
 than I had imagined, but microbiology and immunology were   been doing that ever since.   keep a work/ life balance?

 oddly fascinating. An Honours year in immunology had me      What is it really like? Frequently tedious. Often frustrating. Hard   I have antibodies to the word ‘passionate’ because it is so over-
 hooked, a PhD followed, and a career in medical research   What do you think is the impact of corneal transplants and   to carry out from nine to five, only on weekdays. Unlikely to   used. I enjoy research but I also love all sorts of things outside of
 seemed probably what I wanted.   increased ophthalmological research on society?   make you materially wealthy and seldom provides job security.   it. I’ve never been one for strict separation of ‘work’ on the one
            It could be ghastly, were it not for occasional exhilarating
 So, in answer to your questions, my ‘journey’, as you put it, was   moments when you suddenly consider something you’ve never   hand and ‘life’ on the other. I prefer to run everything together
 indeed linear, at least as viewed from the outside – but from the   thought of before, or for the interactions with colleagues and   and this works for me: it’s all good. Having said that, factoring in
 inside, it seemed that there were many decisions over which to   students that spark a different approach to a problem.  a couple of weeks each year when (and where) I can completely
 agonise.                                                      disconnect keeps me sane.
            A typical day? For early and mid-career researchers, there
            probably isn’t one, because if you knew the answer to the   Have you had any lifelong goals? If so, can you reflect on what
 Do you have a best memory of JCH? Any advice for incoming   problem, then it wouldn’t be research, and you must stay   they are and how you have pursued them?
 freshers or recent JCH alumni?
            flexible. Although so much is made of ‘the scientific method’,   No, other than to try to be a better friend and mentor because
 JCH was a women’s college during my three years of residence.   that method is really there to provide underlying structure,   I’ve been so fortunate myself in having, and having had, such
 Evening dinners in Hall – and the terrible coffee afterwards   rigour and an ethical framework. Reality is that research doesn’t   good friends and generous mentors. I do think I’ve always been
 – are perhaps the clearest memories. I made many friends   necessarily progress in a straight line and is often quite messy.   happy to grasp opportunities as they present themselves, to see
 amongst my year group, and we would sit together around the   Things go unexpectedly wrong all the time. If you are an   where they lead.
 long tables and describe our vastly different experiences, on   experimentalist, having green fingers and reasonable problem-
 and off campus. Most of these young women were undertaking   solving skills do help. For dry laboratory research, a basic grasp   Do you have any other advice or wisdom for the students of
 different courses from my own and I learnt so much.  of statistics and the concept of bias are very useful.   Janet Clarke Hall?
 Advice? I can only report that living in a university college is a   A successful corneal transplant  For more senior researchers, especially at the professorial     I’m not the one to ask for advice because I doubt that I’m wise.
 gift and that the friendships made there can be enduring. So,   From my perspective as an onlooker, corneal transplantation   level, a typical day might include a faculty meeting (seldom   I would point out that I’ve found that very few of the career
 enjoy – and take advantage of the time that you don’t spend in   can be life-changing. The procedure can restore vision to   entertaining but if you aren’t in the room, you can’t contribute),   decisions that one faces before, during or after graduation are ever
 travelling to campus.  catch-ups with students, research assistants and postdocs   seriously limiting. There are always alternative ways of reaching a
 those who are severely visually impaired. In some cases, it   (often challenging but valuable) and, probably, a few hours in
    significantly reduces pain, and in others it can save an eye from   the evening working on a manuscript or grant application or   goal. The cliche runs that fortune favours the brave. Maybe good
                                                                                    Bjork performing dressed as DNA
 being entirely lost.   both.                                  luck also follows those who try to be as well prepared as possible?
 8  L u ce    Number 23  2024                                                                   Janet Clar ke Hall  9
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