Page 26 - Physiology and Pathophysiology MNU 2024-2025 نظرى

Clinical pharmacy 2024/2025 Level 2 Pharm D Physiology and Pathophysiology (MD303)

• PNMT catalyzes the conversion of norepinephrine to epinephrine, a step that,

requires cortisol from the nearby adrenal cortex.

Types of ganglia in Sympathetic NS

Paravertebral ganglia Collateral (prevertebral) ganglia

➢ Double row of sympathetic ganglia • Sympathetic ganglia which lie between

located on either side of the spinal the paravertebral ganglia and the target

cord. organ.

➢ Ganglia within each row are

interconnected ➔ forming • The ANS nerves that innervate the pelvic

sympathetic chain of ganglia parallels viscera continue through the

the spinal cord. paravertebral ganglia without synapsing.

• They form splanchnic nerves that

o Divergence: Preganglionic fiber synapse in collateral ganglia.

branch to synapse with numerous • Include:

postganglionic neurons a. Celiac ganglia

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