Page 206 - Phytochemistry 2 (06-PG 605)
P. 206
VI-Miscellaneous bitters
1- Humulone, lupulone
They contribute to the bitterness of hops extract
humulone exerts bacteriostatic action ( topical).
Lupulone has sedative activity.
Hops extract is used in Europe as OTC sedative preparation
Humulone lupulone
O O CH3
CH3
prenyl
HO
HO OH
OH O prenyl
prenyl CH3
CH3
O OH
prenyl prenyl
