Page 166 - COMMUNITY PHARMACY PRACTICE
P. 166

02/04/2024

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Corticosteroids ……inhalations or tablets?

     v Corticosteroid is better to be given in form of inhalation as they
         have many side effect

                  Inhalation                   Tablets
Low dose Ex (ventolin=0.1mg/dose)
                                   Need high dose(ventolin
                                     =2mg of salbutamol)

Rapid onset of action , avoid first pass Suffering from the first pass

effect                             effect

Less side effect .                 More side effect

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    Why Inhalation (ICS) is Preferred?

      Inhaled corticosteroids are the most
      effective medicine for long-term control of
      asthma in most people.
     Less Systemic absorption than Tablets, so
     less side effects.
     The least amount of medicine that controls
     the asthma symptoms is used.(small dose)
     Local Effect on the lungs.(targeting)
     Rapid onset of action.
     Good in case of poorly oral absorption drug
     Better stability of the product(aerosols)

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