Page 67 - Pharmaceutics III_ 02-06-01304_Fall 2025_ Pharm D_Electronic book

Tablet Packaging Requirements:
Primary Packaging:

• Direct contact with dosage form.
o Blisters (PVC, PVDC, aluminum).
o Bottles (glass, HDPE).
o Foil strips.

Secondary Packaging:
• Cartons, outer boxes, inserts for information.

Functions:
• Protection, containment, convenience, identification.

Packaging Materials:
1. Glass:
o Type I (borosilicate): for injectables and hygroscopic products.
o Type II (treated soda-lime).
o Type III (ordinary soda-lime).
o Amber color filters UV light.
2. Plastic:
o HDPE, LDPE, polypropylene, PET.
o Lightweight, resistant to breakage.
o Disadvantage: permeability to gases and moisture.
3. Metal foils: aluminum.
4. Paper and laminates: for blister backing.

Child-Resistant Packaging:
Required for hazardous medications.
Uses push-through blisters, locking caps.
Tamper-Evident Packaging:

• Shrink bands, seals, or printed wrappers to indicate opening.

Pharmaceutical Stability – Shelf Life Estimation:

66