Page 296 - Applied Pharmacognosy
P. 296

• The situation was resolved by generating the
  diterpenoid portion 10-deacetylbaccatin III
  (10 DAB III) ) of the paclitaxel molecule by
  growing available ornamental Taxus species
  (the European Yew, T. baccata).

    OH                O OH

                  10

OH

    OH                                        O
                          H

                                 OAc

                      OC Oph

    10-DAB

                                                 295
   291   292   293   294   295   296   297   298   299   300   301