Page 301 - Applied Pharmacognosy
P. 301

Preparation of taxol

• Taxol is prepared by coupling 10-DAB III and the N-benzoyl-B-
  phenylisoserine side chain.

    OH               O OH

                 10                                     O

OH                                            Ph
                                                                NH
                                           O                        O
                        H
    OH
                               OAc
                                                                                OH
                     OC Oph                   Ph

                                                               OH

    10-DAB

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