Page 299 - Applied Pharmacognosy
P. 299
Large scale and economic
semi synthesis of Taxol
• The most demanding portion of Taxol semi- synthesis is:
• The tetracyclic diterpene moiety
• 10 - deacetylbaccatin III (10-DAB III)
• It is readily extracted from the leaves of
Taxus baccata (European Yew) in high yields of 1g/kg.
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