Page 138 - Pharmaceutics IV (02-06-01305)

Ophthalmic DD: dosage forms

Ocular drug delivery systems

Implants
• Biodegradable systems have been developed for intracameral and

intravitreal placement.
• They typically consist of a homogeneous polymeric pellet containing a

therapeutic agent/drug and biodegradable polymer

269

Ophthalmic DD: dosage forms

Ocular drug delivery systems

Ocular insert
• They are sterile drug-impregnated microdevices, placed in or around

the eye for the release of therapeutic drugs over a prolonged duration.
• They are designed for placement in the cul-de-sac, conjunctival sac,

or punctum of the eye.

270 135

Salma E. EL-Habashy