Page 16 - Pharmaceutics IV (02-06-01305)
P. 16
Parenterals: Routes Intravenous (IV)
Why infusions?
The problem with infusion is it takes a few hours to achieve a steady
state. It is often best to start with a bolus injection to cover the first few
hours before the infusion achieves its steady level.
25
Parenterals: Routes Intravenous (IV)
Why infusions?
• By altering the infusion rate, it is possible to titrate the dose against
the effect required, e.g. controlling blood pressure
• Slow IV infusion of a drug product is useful to avoid side effects,
such as chemotherapeutic agents for cancer therapy.
26 13
Salma E. EL-Habashy